Benzyl benzoate, with the CAS number 120 - 51 - 4, is an organic compound. Its molecular formula is C14H12O2, and it has a molecular weight of approximately 212.24 g/mol. It appears as a colorless to pale - yellow liquid with a faint, aromatic odor. This product is typically produced in large quantities in factories, ensuring a stable supply at the best price. Benzyl benzoate is insoluble in water but soluble in organic solvents such as ethanol, ether, and chloroform. It has a boiling point of around 323 - 324 °C and a density of about 1.118 g/cm³ at 25 °C.
1. **Pharmaceutical Field**: Benzyl benzoate is widely used as a scabicide and pediculicide. It can be formulated into topical creams or lotions to treat scabies and head lice infestations. The compound works by suffocating the parasites, effectively eliminating them from the skin and hair.
2. **Fragrance and Flavor Industry**: It serves as a fixative in perfumes and colognes. By helping to blend and retain the fragrance notes, it enhances the longevity and stability of the scent. In the flavor industry, it can be used to impart a mild, sweet - floral flavor to certain food products.
3. **Chemical Intermediate**: Benzyl benzoate is an important intermediate for the synthesis of other organic compounds. It can be used in the production of plasticizers, solvents, and some specialty chemicals.
1. **Topical Application in Medicine**: For scabies treatment, the skin should be thoroughly cleaned and dried before application. The benzyl benzoate cream or lotion is then applied evenly over the entire body from the neck down, paying special attention to areas such as folds of the skin, between fingers and toes, and under the nails. It should be left on the skin for the recommended time, usually 24 - 48 hours, and then washed off. For head lice, the product is applied to the scalp and hair, left for a specified period, and then the hair is combed with a fine - tooth comb to remove dead lice and nits.
2. **In the Fragrance and Flavor Industry**: When used in perfume formulation, it is added in small amounts during the blending process. The exact quantity depends on the desired fragrance profile. In the flavor industry, it should be used in strict accordance with the allowed usage levels and safety regulations.
1. **Medical Case**: A patient presented with severe scabies infestation. After being prescribed a benzyl benzoate - based cream, the patient followed the application instructions carefully. Within 48 hours of the first application, the itching and redness started to subside significantly. After a second application a week later, the scabies were completely eradicated, and the patient's skin returned to normal.
2. **Fragrance Case**: A new perfume brand was struggling to achieve a long - lasting and well - balanced scent. By adding benzyl benzoate as a fixative during the formulation process, the fragrance became more stable. The top, middle, and base notes blended harmoniously, and the perfume's longevity increased from a few hours to over 12 hours, leading to positive customer feedback and increased sales.
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