3-Chlorobenzaldehyde CAS 587-04-2: High-Quality Chemical Intermediate at Competitive Prices
Table of Contents
1. Product Overview
3-Chlorobenzaldehyde (CAS 587-04-2) is a versatile aromatic aldehyde with the molecular formula C7H5ClO. Key specifications include:
- Molecular Weight: 140.57 g/mol
- Appearance: Clear colorless to pale yellow liquid
- Purity: ≥98%
- Melting Point: 8-10°C
- Boiling Point: 213-215°C
- Density: 1.241 g/cm³
2. Applications of 3-Chlorobenzaldehyde
This organochlorine compound serves as a critical intermediate in:
- Pharmaceutical synthesis (e.g., antihypertensive drugs, antifungal agents)
- Agrochemical production (herbicides, pesticides)
- Dye and pigment manufacturing
- Flavor and fragrance industries
- Organic research and chemical development
3. Usage Guidelines
Handling & Storage
- Store in cool (<20°C), dry, ventilated areas away from light
- Use corrosion-resistant containers (stainless steel or glass)
- Keep away from strong oxidizers and bases
Safety Precautions
- Wear PPE: chemical goggles, gloves, and lab coat
- Use in fume hoods with proper exhaust systems
- Follow GHS guidelines: H302 (Harmful if swallowed)
4. Practical Use Cases
Case 1: Pharmaceutical Intermediate
In the synthesis of Clobenzorex (appetite suppressant):
- 3-Chlorobenzaldehyde undergoes condensation with amphetamine derivatives
- Intermediate purified via vacuum distillation
- Final product yield: 82-85% under optimized conditions
Case 2: Agrochemical Production
Manufacture of chlorobenzilate fungicide:
- Reaction with ethylene glycol under acidic catalysis
- 12-hour reflux at 110°C
- Post-reaction neutralization yields 92% pure product
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