Polyhexamethylene biguanide hydrochloride (PHMB), with the CAS number 32289-58-0, is a well - known and effective antimicrobial agent. It exists in the form of a white to off - white powder. PHMB has a high solubility in water, which makes it easy to formulate into various solutions. The molecular formula of PHMB is (C8H17N5·HCl)n, and its molecular weight varies depending on the degree of polymerization.
PHMB is stable under normal storage conditions, but it is recommended to store it in a cool, dry place away from direct sunlight and strong oxidizing agents. The purity of our factory - supplied PHMB is carefully controlled to ensure high - quality performance, usually with a purity of over 98%.
1. **Disinfection and Sanitization**: PHMB is widely used in the field of disinfection. It can be added to disinfectant solutions for surface cleaning in hospitals, schools, and public places. It effectively kills a wide range of bacteria, fungi, and viruses, helping to prevent the spread of infectious diseases.
2. **Personal Care Products**: In personal care products such as shampoos, body washes, and hand sanitizers, PHMB acts as a preservative and antibacterial agent. It helps to keep the products free from microbial contamination and also provides antibacterial protection to the skin and hair.
3. **Water Treatment**: PHMB is used in water treatment applications, including swimming pools, spa waters, and industrial water systems. It can control the growth of algae, bacteria, and other microorganisms in water, maintaining water quality and safety.
4. **Wound Care**: In the medical field, PHMB is used in wound dressings and antiseptic solutions for wound care. It has a mild antibacterial effect and can promote wound healing by preventing infection.
1. **Disinfectant Solutions**: Dissolve the appropriate amount of PHMB in water according to the required concentration. For general surface disinfection, a concentration of 0.1% - 0.5% is usually sufficient. Use a spray bottle or a cloth to apply the solution to the surface and let it sit for a few minutes before wiping it off.
2. **Personal Care Products**: When formulating personal care products, add PHMB during the manufacturing process at a recommended concentration of 0.05% - 0.2%. Ensure thorough mixing to achieve uniform distribution in the product.
3. **Water Treatment**: Calculate the amount of PHMB needed based on the volume of water. For swimming pools, add PHMB at a rate of 1 - 5 ppm (parts per million). Continuously monitor the water quality and adjust the dosage as needed.
4. **Wound Care**: For wound dressings, use a PHMB - containing solution to moisten the dressing, or apply a PHMB - based antiseptic directly to the wound. Follow the medical professional's instructions for frequency of application.
1. **Hospital Surface Disinfection**: A large - scale hospital in the United States switched to using a PHMB - based disinfectant for surface cleaning. After a period of use, the hospital saw a significant reduction in the incidence of hospital - acquired infections. The PHMB - based solution was able to effectively kill common pathogens such as Staphylococcus aureus and Escherichia coli on high - touch surfaces, improving the overall hygiene of the hospital environment.
2. **Swimming Pool Water Treatment**: A public swimming pool in Europe started using PHMB for water treatment. By maintaining a stable concentration of PHMB in the pool water, the pool was able to keep the water clear and free from algae growth throughout the swimming season. The swimmers also reported fewer skin and eye irritations compared to the previous chlorine - based treatment method.
3. **Personal Care Product Formulation**: A cosmetic company incorporated PHMB into its new line of shampoos. The product was well - received by consumers as it effectively prevented dandruff caused by fungal infections and provided long - lasting freshness to the hair. The addition of PHMB also extended the shelf - life of the shampoo without the need for other harsh preservatives.
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