High Quality 5-Norbornene-2-carboxylic acid CAS 120-74-1 With Best Price is a well - known chemical product. The CAS number 120 - 74 - 1 uniquely identifies this compound. In terms of its chemical structure, 5 - Norbornene - 2 - carboxylic acid is a bicyclic organic acid. It has a norbornene ring system with a carboxylic acid functional group attached at the 2 - position.
Regarding its physical properties, it usually appears as a white to off - white solid. It has a certain melting point and solubility profile. The melting point of this compound is typically in a specific range that can be precisely determined through laboratory analysis. Its solubility in different solvents, such as water, ethanol, and other organic solvents, varies, which is an important parameter for its application and handling.
5 - Norbornene - 2 - carboxylic acid has a wide range of uses in the chemical and pharmaceutical industries. In the chemical field, it serves as a key intermediate for the synthesis of various polymers. Due to the presence of the norbornene double bond and the carboxylic acid group, it can participate in different types of polymerization reactions, such as ring - opening metathesis polymerization (ROMP). Polymers synthesized from this compound may have unique physical and chemical properties, such as high mechanical strength, good thermal stability, and excellent solubility in some solvents, making them suitable for applications in coatings, adhesives, and composite materials.
In the pharmaceutical industry, it can be used as a starting material for the synthesis of certain drugs. The carboxylic acid group can be further modified to form various esters, amides, or other derivatives, which may have potential biological activities, such as antibacterial, antiviral, or anti - inflammatory effects.
When using High Quality 5 - Norbornene - 2 - carboxylic acid, safety precautions should be strictly followed. First, appropriate personal protective equipment, such as gloves, goggles, and lab coats, should be worn. The product should be stored in a cool, dry, and well - ventilated place away from sources of ignition and oxidizing agents.
In the laboratory, when dissolving the product, select an appropriate solvent according to its solubility characteristics. For example, if a polar solvent is required, ethanol or water - alcohol mixtures can be used; if a non - polar solvent is needed, hexane or toluene may be considered. When using it in a reaction, accurately measure the amount of the product according to the reaction stoichiometry to ensure the smooth progress of the reaction.
Case 1: Polymer Synthesis
In a research project on the development of high - performance coatings, a team of chemists used 5 - Norbornene - 2 - carboxylic acid as a monomer in ROMP. They first prepared a metathesis catalyst and then added the 5 - Norbornene - 2 - carboxylic acid to the reaction system in a specific molar ratio. The reaction was carried out under an inert gas atmosphere (such as nitrogen) at a controlled temperature. After a certain reaction time, a polymer with a desired molecular weight and structure was obtained. The resulting polymer was then formulated into a coating, which showed excellent adhesion, hardness, and chemical resistance on the substrate.
Case 2: Pharmaceutical Intermediate Synthesis
A pharmaceutical company was working on the development of a new antibacterial drug. 5 - Norbornene - 2 - carboxylic acid was used as a starting material. They first converted the carboxylic acid group into an acyl chloride group through a reaction with thionyl chloride. Then, the acyl chloride was reacted with an amine compound to form an amide derivative. After a series of purification and modification steps, the final compound showed promising antibacterial activity in in vitro tests.
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