The product, Factory Supply 4-Fluorophenol Cas 371-41-5 With Good Price, is a chemical compound with significant industrial and research applications. The CAS number 371 - 41 - 5 uniquely identifies this chemical in the global chemical registry.
Chemical formula: C₆H₅FO. Molecular weight: approximately 112.1 g/mol. It is a white to light - yellow crystalline solid at room temperature. The melting point of 4 - Fluorophenol is around 45 - 47°C, and the boiling point is about 185 - 186°C. It is sparingly soluble in water but soluble in many organic solvents such as ethanol, ether, and acetone.
1. **Pharmaceutical Industry**: 4 - Fluorophenol serves as a crucial intermediate in the synthesis of various pharmaceutical drugs. It can be used to introduce the fluorophenol moiety into drug molecules, which can enhance the bioactivity, metabolic stability, and pharmacokinetic properties of drugs. For example, it is used in the synthesis of some anti - inflammatory and anti - cancer drugs.
2. **Agrochemical Industry**: In the production of pesticides and herbicides, 4 - Fluorophenol is an important raw material. The introduction of the fluorophenol group can improve the efficacy and selectivity of agrochemicals, helping to protect crops from pests and weeds more effectively.
3. **Material Science**: It can be used in the synthesis of high - performance polymers and specialty chemicals. The presence of the fluorine atom in 4 - Fluorophenol can endow materials with unique properties such as good chemical resistance, thermal stability, and low surface energy.
1. **Storage**: Store 4 - Fluorophenol in a cool, dry, and well - ventilated place. Keep it away from sources of ignition, heat, and direct sunlight. It should be stored in a tightly closed container to prevent moisture absorption and contamination.
2. **Handling**: When handling 4 - Fluorophenol, appropriate personal protective equipment (PPE) should be worn, including safety goggles, chemical - resistant gloves, and a lab coat. Avoid inhalation of dust or vapors. In case of contact with skin or eyes, immediately rinse with plenty of water and seek medical attention if necessary.
3. **Reaction Conditions**: In chemical synthesis, the reaction conditions need to be carefully controlled. The reaction temperature, pressure, and reaction time should be optimized according to the specific reaction system. Usually, 4 - Fluorophenol reacts with other reagents under the action of catalysts or under certain heating or cooling conditions.
**Pharmaceutical Synthesis Case**:
In a research project on developing a new anti - inflammatory drug, 4 - Fluorophenol was used as a key intermediate. The first step was to react 4 - Fluorophenol with a specific carboxylic acid under the action of a coupling agent and a base. The reaction was carried out in an organic solvent at a temperature of 80°C for 6 hours. After purification by column chromatography, an intermediate product was obtained. This intermediate was further reacted with other reagents through a series of steps to finally synthesize the target anti - inflammatory drug. The introduction of the fluorophenol group improved the drug's affinity for the target receptor, enhancing its anti - inflammatory effect.
**Agrochemical Synthesis Case**:
A company was developing a new herbicide. 4 - Fluorophenol was reacted with a halogenated alkane in the presence of a base to form an ether - containing intermediate. This intermediate was then further functionalized through a multi - step reaction to obtain the final herbicide product. The presence of the fluorophenol group increased the herbicide's selectivity towards weeds, while having less impact on the crops, resulting in a more effective and environmentally friendly herbicide.
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Este é o William, Diretor Executivo da Zhishang Chemical Co., Ltd.
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