Hydroxypropyl Methylcellulose Phthalate (HPMCP), with the CAS number 9050 - 31 - 1, is a cellulose derivative. It is a white to off - white powder. The product is supplied by our factory at a low price, which makes it an attractive option for various industries.
Some key parameters of this product include: its molecular weight varies depending on the specific grade. The substitution degree of hydroxypropyl and methyl groups, as well as the degree of phthaloyl substitution, can influence its physical and chemical properties. HPMCP is insoluble in water and acidic solutions but soluble in alkaline solutions above a certain pH value, usually around pH 5.5 - 6.0.
In the pharmaceutical industry, HPMCP is widely used as an enteric coating material. Enteric coatings are designed to protect drugs from the acidic environment of the stomach and release them in the more alkaline environment of the intestines. This helps to improve the stability of drugs, reduce irritation to the stomach, and control the drug release rate. It can also be used as a binder in tablet formulations, enhancing the cohesion of the tablet ingredients.
In the food industry, it can be used as a thickener, stabilizer, and emulsifier. It can improve the texture and stability of food products, such as sauces and dressings. In addition, it can be used as a film - forming agent for food packaging, providing a barrier against moisture and oxygen.
When using HPMCP as an enteric coating material, first, a coating solution needs to be prepared. Dissolve the HPMCP powder in a suitable organic solvent or a mixture of solvents, such as a combination of ethanol and water. The concentration of the solution depends on the coating equipment and the desired coating thickness. Usually, a concentration of 5% - 15% (w/v) is used.
Add appropriate plasticizers to the solution to improve the flexibility and adhesion of the coating. Common plasticizers include triethyl citrate and dibutyl phthalate. Then, use a coating machine, such as a pan coater or a fluid - bed coater, to apply the coating solution onto the tablets or granules. The coating process should be carried out under controlled temperature and humidity conditions to ensure uniform coating.
When using it as a binder in tablets, mix the HPMCP powder with other tablet ingredients in a suitable mixer. The amount of HPMCP used depends on the nature of the ingredients and the required tablet hardness. Generally, 2% - 5% (w/w) of HPMCP is added.
Case 1: A pharmaceutical company was developing a new enteric - coated tablet for a drug that was sensitive to stomach acid. They used our HPMCP as the enteric coating material. By optimizing the coating solution formulation and process parameters, they achieved a uniform and stable enteric coating. The tablets passed the in - vitro dissolution tests, showing that the drug was released only in the intestinal environment, which improved the efficacy and safety of the drug.
Case 2: A food company was looking for a natural thickener and stabilizer for their salad dressing. They chose our HPMCP. After adding an appropriate amount of HPMCP to the dressing formula, they found that the dressing had a better texture, reduced oil separation, and a longer shelf - life. Consumers also reported a more pleasant mouthfeel.
If you have any questions about our Factory Supply Hydroxypropyl Methylcellulose Phthalate Cas 9050 - 31 - 1 With Low Price, please feel free to contact us. Our email address is info@vivalr.com, and our phone number is (86) 15866781826.
Este é o William, Diretor Executivo da Zhishang Chemical Co., Ltd.
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