The product, Factory Supply sorafenib tosylate cas 84461 - 73 - 0 With Best Price, is a significant pharmaceutical compound. Sorafenib tosylate is the tosylate salt form of sorafenib, a small molecule with antineoplastic activity.
CAS Number: 84461 - 73 - 0. The chemical formula of sorafenib is C₂₁H₁₆ClF₃N₄O₃, and when combined with tosylate, it forms a stable compound with specific physical and chemical properties. It usually appears as a white to off - white powder. Solubility: It has a certain solubility in organic solvents under specific conditions, which is crucial for its formulation and delivery in the medical field.
Sorafenib tosylate is mainly used in the field of oncology. It acts as a multi - kinase inhibitor. It can inhibit the activity of several receptor tyrosine kinases (RTKs), which are involved in tumor growth, angiogenesis, and metastasis.
In the treatment of advanced renal cell carcinoma (RCC), it has shown significant efficacy. By blocking the signaling pathways related to angiogenesis, it can cut off the blood supply to the tumor, thereby inhibiting tumor growth and spread. Additionally, it is also used in the treatment of advanced hepatocellular carcinoma (HCC). It can interfere with the growth signals of cancer cells and slow down the progression of the disease.
Sorafenib tosylate is usually administered orally. The recommended dosage for patients with advanced RCC or HCC is typically 400 mg (two 200 - mg tablets) twice daily, taken on an empty stomach (at least one hour before or two hours after a meal).
The treatment course should be determined by the doctor according to the patient's condition, physical condition, and response to the drug. During the treatment process, patients should take the medicine regularly and on time. Do not increase or decrease the dosage without permission, as this may affect the treatment effect or cause adverse reactions.
Case 1: A 55 - year - old male patient was diagnosed with advanced renal cell carcinoma. After traditional treatment methods had limited effectiveness, the doctor prescribed sorafenib tosylate. The patient took 400 mg twice a day as directed. After 3 months of treatment, imaging examinations showed that the size of the tumor had significantly decreased, and the patient's symptoms such as abdominal pain and fatigue were also alleviated. The patient continued the treatment under the doctor's supervision, and the disease was effectively controlled for a long time.
Case 2: A 60 - year - old female patient with advanced hepatocellular carcinoma started taking sorafenib tosylate. Although the disease had advanced, after starting the medication, her liver function indicators gradually improved, and the rate of tumor growth slowed down. Her quality of life also improved, and she was able to carry out normal daily activities to a certain extent.
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