1-Fluoronaphthalene, with the CAS number 321-38-0, is a high - quality chemical compound. It appears as a colorless to pale - yellow liquid at room temperature. The chemical formula of 1 - Fluoronaphthalene is C₁₀H₇F, and it has a molecular weight of approximately 146.16 g/mol. This compound has a melting point around - 29 °C and a boiling point of about 214 - 215 °C. It has a density of around 1.139 g/cm³ at 25 °C. High - quality 1 - Fluoronaphthalene with low price is ideal for various industrial and research applications due to its relatively stable chemical properties and well - defined physical characteristics.
1. **Organic Synthesis**: It serves as a crucial intermediate in organic synthesis. It can participate in a variety of reactions, such as substitution reactions, for the production of more complex fluorinated organic compounds. These fluorinated compounds are often used in the pharmaceutical industry, as fluorine - containing drugs can have enhanced biological activities, improved pharmacokinetic properties, and better metabolic stability.
2. **Material Science**: In material science, 1 - Fluoronaphthalene can be used to modify polymers and other materials. The fluorine atom in the molecule can improve the material's chemical resistance, surface properties, and thermal stability, making it suitable for applications in coatings, adhesives, and advanced composite materials.
3. **Research and Development**: As a research reagent, it is used in academic and industrial research laboratories. Scientists can use it to study the reaction mechanisms of fluorine - containing compounds and explore new synthetic routes for potential new materials or drugs.
When using 1 - Fluoronaphthalene, it is essential to follow proper safety procedures. Always wear appropriate personal protective equipment, including safety goggles, gloves, and a lab coat.
1. **Storage**: Store 1 - Fluoronaphthalene in a cool, dry place away from direct sunlight and sources of ignition. Keep it in a tightly - sealed container to prevent evaporation and contamination.
2. **Handling**: When handling the compound, use a fume hood to ensure good ventilation. Measure the required amount carefully using appropriate measuring tools, such as pipettes or burettes.
3. **Reaction Conditions**: In organic synthesis, the reaction conditions need to be carefully controlled. The reaction temperature, pressure, and reaction time should be determined according to the specific reaction requirements. Appropriate catalysts and solvents may also be needed to promote the reaction.
1. **Pharmaceutical Research Case**: A pharmaceutical research team was aiming to develop a new anti - cancer drug. They used 1 - Fluoronaphthalene as a starting material in a multi - step synthesis. First, they carried out a substitution reaction on the fluoronaphthalene ring, introducing a specific functional group. Through subsequent reactions, they successfully synthesized a novel fluorinated compound. In in - vitro experiments, this compound showed significant inhibitory effects on cancer cell growth. After further optimization and pre - clinical studies, it is expected to enter the clinical trial stage.
2. **Material Modification Case**: A materials science company was looking to improve the performance of a polymer coating. They added 1 - Fluoronaphthalene during the polymerization process. The resulting polymer coating had better water - repellency, chemical resistance, and scratch resistance. This new coating was then used in automotive and aerospace applications, where high - performance coatings are required.
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