The product is High Quality L-Glutamic acid 5-tert-butyl ester with the CAS number 2419-56-9. It is well - known for its high quality and comes with the best price in the market. The chemical formula of L - Glutamic acid 5 - tert - butyl ester is (C_{9}H_{17}NO_{4}). It appears as a white to off - white crystalline powder. The melting point of this product typically ranges from 104 - 108°C. It has a specific optical rotation, which is an important characteristic for determining its purity and quality. The product is usually stored at room temperature, away from light and moisture, and should be kept in a well - sealed container to maintain its stability.
1. **Pharmaceutical Industry**: L - Glutamic acid 5 - tert - butyl ester is an important intermediate in the synthesis of various pharmaceutical compounds. It can be used in the production of drugs that target the nervous system, as it is related to the metabolism of neurotransmitters. For example, it can be involved in the synthesis of some anti - anxiety and antidepressant drugs.
2. **Peptide Synthesis**: In the field of peptide chemistry, this product serves as a valuable building block. It can be incorporated into peptide chains during solid - phase or solution - phase peptide synthesis. The tert - butyl ester group can be selectively removed under specific reaction conditions, allowing for the controlled synthesis of complex peptides with precise sequences.
3. **Biochemical Research**: Researchers use L - Glutamic acid 5 - tert - butyl ester to study biochemical pathways and enzyme reactions. It can be used as a substrate or inhibitor in enzymatic assays to understand the mechanism of action of certain enzymes involved in amino acid metabolism.
1. **Weighing**: When using this product, first ensure that you are using a calibrated weighing balance. Wear appropriate personal protective equipment, such as gloves and a lab coat. Weigh the required amount of L - Glutamic acid 5 - tert - butyl ester accurately according to your experimental or production needs.
2. **Dissolution**: The product can be dissolved in common organic solvents such as dichloromethane, ethanol, or dimethylformamide (DMF). The choice of solvent depends on the subsequent reaction or application. Stir the solution gently until the product is completely dissolved.
3. **Reaction Conditions**: If using it in a chemical reaction, carefully control the reaction conditions such as temperature, pH, and reaction time. For example, in peptide synthesis, the coupling reaction usually requires specific coupling reagents and a controlled temperature environment to ensure high - yield and high - purity product formation.
1. **Case 1: Pharmaceutical Synthesis**: A pharmaceutical company was synthesizing a new anti - anxiety drug. They used L - Glutamic acid 5 - tert - butyl ester as an intermediate. First, they weighed 5 grams of the product accurately using an analytical balance. Then, they dissolved it in 50 mL of dichloromethane. After that, they added a specific coupling reagent and other reactants under strictly controlled temperature (- 20°C to 0°C) and pH (around 7 - 8) conditions. Through a series of reaction steps, they successfully obtained the target pharmaceutical compound with a yield of 70%. The final product was then purified and tested for its efficacy, and it showed promising results in pre - clinical trials.
2. **Case 2: Peptide Synthesis in Research**: A research group was synthesizing a short peptide with a specific sequence. They incorporated L - Glutamic acid 5 - tert - butyl ester into the peptide chain during solid - phase peptide synthesis. They swelled the resin in DMF, added the activated amino acid (L - Glutamic acid 5 - tert - butyl ester) along with a coupling agent, and let the reaction proceed for 2 hours at room temperature. After several cycles of coupling and deprotection steps, they obtained the desired peptide. The purity of the peptide was analyzed by high - performance liquid chromatography (HPLC), and it was found to be 95%, which was suitable for further biological studies.
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Este é o William, Diretor Executivo da Zhishang Chemical Co., Ltd.
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