
Calcium Folinate with CAS number 1492-18-8 is a well - known chemical compound. It is a calcium salt of folinic acid, which is a form of folate. The molecular formula of Calcium Folinate is C₂₀H₂₃CaN₇O₇, and its molecular weight is approximately 511.5 g/mol.
Factory - supplied Calcium Folinate is of high purity, ensuring the best quality for various applications. The product is usually presented as a white to yellowish - white crystalline powder. It is soluble in water, which makes it convenient for different uses. The product is stored under recommended conditions to maintain its stability and efficacy.
1. **Medical Field**: Calcium Folinate is widely used in medicine. It is an important antidote for the toxicity of folic acid antagonists such as methotrexate. In cancer chemotherapy, when high - dose methotrexate is used, Calcium Folinate is administered to rescue normal cells from the cytotoxic effects of methotrexate, reducing the side - effects on the bone marrow and gastrointestinal tract.
2. **Nutritional Supplements**: It can also be used as a nutritional supplement. Folinic acid is involved in many biochemical reactions in the body, including DNA synthesis, repair, and methylation. As a calcium salt, it is more bioavailable and can be used to supplement folate in cases where normal folate metabolism is impaired.
1. **Medical Use**: In a medical setting, the dosage of Calcium Folinate is determined by a healthcare professional based on various factors such as the patient's age, weight, medical condition, and the type of chemotherapy being used. It is usually administered either intravenously or intramuscularly. For example, in methotrexate rescue, the initial dose may be given 24 hours after the start of methotrexate infusion, and subsequent doses are adjusted according to the patient's response and methotrexate plasma levels.
2. **Nutritional Use**: When used as a nutritional supplement, the dosage is usually lower. It can be taken orally. It is recommended to follow the instructions on the product label or consult a healthcare provider for the appropriate dosage. It is important to take Calcium Folinate with food to enhance its absorption.
Case 1: In a large - scale cancer treatment center, a patient with osteosarcoma was undergoing high - dose methotrexate chemotherapy. Without appropriate rescue, high - dose methotrexate can cause severe bone marrow suppression and gastrointestinal toxicity. Calcium Folinate was administered at a carefully calculated dosage starting 24 hours after the methotrexate infusion. The patient had significantly fewer side - effects compared to historical cases without Calcium Folinate rescue. The bone marrow function was maintained at a relatively normal level, and the patient was able to tolerate subsequent chemotherapy cycles better.
Case 2: A group of elderly patients with a history of poor folate absorption due to gastrointestinal problems were given Calcium Folinate as a nutritional supplement. After a few months of supplementation, blood tests showed an improvement in folate levels in their bodies. The patients also reported an increase in energy levels and a general improvement in well - being.
If you have any questions or need further information about Factory Supply Calcium Folinate Cas 1492 - 18 - 8, please feel free to contact us:
Correio eletrónico: info@vivalr.com
Telefone: (86) 15866781826

Este é o William, Diretor Executivo da Zhishang Chemical Co., Ltd.
Bem-vindo a visitar a nossa fábrica. Como o principal fabricante de produtos químicos, temos nos esforçado para a qualidade do produto, inovação, P & D e atendimento ao cliente nos últimos 7 anos. Nos próximos 10 anos ou mais, estamos empenhados em nos tornarmos o fornecedor de produtos químicos mais confiável do mundo, criando uma marca internacional bem conhecida e de confiança dos clientes, com o espírito de "um metro de largura, dez mil metros de profundidade", continuamos a nos concentrar na pesquisa e desenvolvimento de produtos, continuamos a nos concentrar no atendimento ao cliente, continuamos a melhorar o sistema de serviço da cadeia de suprimentos, para criar uma equipe profissional de serviços de fornecimento de produtos químicos, para alcançar uma cooperação de longo prazo ganha-ganha. Por favor, não hesite em contactar-nos se tiver alguma dúvida.











