Phenylhydrazine, with the CAS number 100 - 63 - 0, is an important organic compound. Its chemical formula is C6H5NHNH2. It appears as a pale yellow to yellow liquid or solid at room temperature. The molar mass of phenylhydrazine is approximately 108.14 g/mol. It has a melting point of about 19 - 21 °C and a boiling point around 243 - 245 °C. Phenylhydrazine is soluble in ethanol, ether, and benzene, but slightly soluble in water. It has a characteristic pungent odor.
When it comes to quality control, the purity of our factory - supplied phenylhydrazine is carefully maintained. Usually, the purity can reach over 99%, which ensures high - performance in various applications. It is stored in a cool, dry, and well - ventilated place, away from sources of ignition and oxidizing agents.
Phenylhydrazine plays a crucial role in the field of organic synthesis. It is widely used as a reagent for the synthesis of indoles. In the preparation of indoles, phenylhydrazine reacts with aldehydes or ketones under specific reaction conditions to form hydrazones, which then undergo a Fischer indole synthesis reaction to yield indole derivatives. These indole derivatives are important intermediates in the synthesis of pharmaceuticals, dyes, and agrochemicals.
It is also used in the analysis of carbohydrates. Phenylhydrazine can react with monosaccharides to form osazones. The formation of osazones has characteristic crystal forms and melting points, which can be used for the identification and differentiation of different carbohydrates in carbohydrate analysis.
When handling phenylhydrazine, it is necessary to wear appropriate personal protective equipment, including chemical - resistant gloves, safety goggles, and a lab coat. In a laboratory setting, when using phenylhydrazine for organic synthesis reactions, precise measurements should be taken. For example, when using it in a Fischer indole synthesis reaction, the appropriate amount of phenylhydrazine and the corresponding aldehyde or ketone are added to a reaction flask, usually in an organic solvent such as ethanol. Then, an acid catalyst is added, and the reaction mixture is heated under reflux for a certain period of time. The progress of the reaction can be monitored by thin - layer chromatography (TLC). After the reaction is completed, the product is separated and purified by appropriate methods such as extraction and recrystallization.
In carbohydrate analysis, a sample solution containing carbohydrates is mixed with phenylhydrazine hydrochloride solution and sodium acetate solution. The mixture is heated in a water bath for a certain time until the osazones are formed. Then, the osazones can be observed under a microscope for identification.
Caso 1: Síntese farmacêutica
A pharmaceutical company was synthesizing a new anti - cancer drug. The key intermediate in the synthesis process was an indole derivative. They used our high - purity phenylhydrazine in the Fischer indole synthesis reaction. By precisely controlling the reaction conditions, such as the molar ratio of phenylhydrazine to the starting aldehyde, reaction temperature, and reaction time, they were able to obtain the desired indole derivative with a high yield of over 80%. This high - quality intermediate was then used in subsequent reactions to successfully synthesize the anti - cancer drug.
Case 2: Carbohydrate Analysis
A food research institution was analyzing the carbohydrate composition of a new type of fruit juice. They used phenylhydrazine to form osazones with the monosaccharides in the fruit juice. By comparing the crystal forms and melting points of the osazones with standard samples, they were able to accurately identify the types of monosaccharides present in the fruit juice, such as glucose and fructose. This information was important for understanding the nutritional value and quality of the fruit juice.
If you have any questions about our Factory Supply Phenylhydrazine Cas 100 - 63 - 0 With Good Price, please feel free to contact us. Our email is info@vivalr.com, and our phone number is (86) 1586678182
Este é o William, Diretor Executivo da Zhishang Chemical Co., Ltd.
Bem-vindo a visitar a nossa fábrica. Como o principal fabricante de produtos químicos, temos nos esforçado para a qualidade do produto, inovação, P & D e atendimento ao cliente nos últimos 7 anos. Nos próximos 10 anos ou mais, estamos empenhados em nos tornarmos o fornecedor de produtos químicos mais confiável do mundo, criando uma marca internacional bem conhecida e de confiança dos clientes, com o espírito de "um metro de largura, dez mil metros de profundidade", continuamos a nos concentrar na pesquisa e desenvolvimento de produtos, continuamos a nos concentrar no atendimento ao cliente, continuamos a melhorar o sistema de serviço da cadeia de suprimentos, para criar uma equipe profissional de serviços de fornecimento de produtos químicos, para alcançar uma cooperação de longo prazo ganha-ganha. Por favor, não hesite em contactar-nos se tiver alguma dúvida.
Portuguese 
English (United States) 
English (Australia) 
Spanish