The product named "Factory Supply Celastrol CAS 34157 - 83 - 0 With Low Price" is a chemical compound. Celastrol, with the CAS number 34157 - 83 - 0, is also known as tripterine. It is extracted from the root bark of Tripterygium wilfordii Hook F, a traditional Chinese medicinal plant.
Chemically, Celastrol has a molecular formula of C₂₉H₃₄O₅ and a molecular weight of approximately 462.58 g/mol. It appears as a yellow - brown to orange - red powder. The product is supplied directly from the factory, which ensures high - quality control and a relatively low price compared to other market sources. The purity of the supplied Celastrol can usually reach up to 98% or higher, depending on the specific requirements of the customer.
2.1 Medicinal Uses: Celastrol has shown a wide range of potential medicinal applications. It has anti - inflammatory properties, which can be used in the treatment of various inflammatory diseases such as rheumatoid arthritis. It also has anti - cancer effects by inducing apoptosis in cancer cells, inhibiting tumor growth and metastasis. Additionally, Celastrol has been studied for its potential in treating neurodegenerative diseases like Alzheimer's and Parkinson's due to its ability to reduce oxidative stress and inflammation in the brain.
2.2 Research Purposes: In scientific research, Celastrol serves as an important tool compound. It can be used to study signal transduction pathways, gene expression regulation, and the physiological and pathological mechanisms of cells. Researchers can use it to explore new therapeutic targets and develop novel drugs.
3.1 For Laboratory Research: When using Celastrol in the laboratory, it is usually dissolved in an appropriate solvent such as dimethyl sulfoxide (DMSO) to prepare a stock solution. The stock solution is then diluted to the desired concentration for cell experiments or animal studies. The specific concentration and dosage should be determined according to the experimental design and the type of cells or animals used.
3.2 For Medicinal Applications: If used for medicinal purposes, the usage and dosage should be strictly in accordance with the doctor's advice. Celastrol may have certain side effects, so it is necessary to monitor the patient's physical condition during the treatment process.
4.1 Cancer Research Case: A research team in a well - known university used Celastrol to treat breast cancer cell lines in vitro. They prepared a Celastrol solution with a concentration of 1 μM and added it to the cell culture medium. After 48 hours of treatment, they found that the proliferation of breast cancer cells was significantly inhibited, and the apoptosis rate increased by 30% compared with the control group. Further in - vivo experiments in mice also showed that Celastrol could effectively inhibit the growth of breast tumors.
4.2 Inflammatory Disease Case: In a clinical trial for rheumatoid arthritis, patients were divided into two groups. One group was treated with Celastrol at a daily dose of 2 mg, and the other group was treated with a placebo. After 3 months of treatment, patients in the Celastrol group showed significant improvement in joint swelling, pain, and morning stiffness. The erythrocyte sedimentation rate and C - reactive protein levels, which are indicators of inflammation, also decreased significantly.
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Este é o William, Diretor Executivo da Zhishang Chemical Co., Ltd.
Bem-vindo a visitar a nossa fábrica. Como o principal fabricante de produtos químicos, temos nos esforçado para a qualidade do produto, inovação, P & D e atendimento ao cliente nos últimos 7 anos. Nos próximos 10 anos ou mais, estamos empenhados em nos tornarmos o fornecedor de produtos químicos mais confiável do mundo, criando uma marca internacional bem conhecida e de confiança dos clientes, com o espírito de "um metro de largura, dez mil metros de profundidade", continuamos a nos concentrar na pesquisa e desenvolvimento de produtos, continuamos a nos concentrar no atendimento ao cliente, continuamos a melhorar o sistema de serviço da cadeia de suprimentos, para criar uma equipe profissional de serviços de fornecimento de produtos químicos, para alcançar uma cooperação de longo prazo ganha-ganha. Por favor, não hesite em contactar-nos se tiver alguma dúvida.
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