{"id":163,"date":"2025-03-07T12:05:11","date_gmt":"2025-03-07T12:05:11","guid":{"rendered":"https:\/\/vivalr.com\/product\/163.html"},"modified":"2025-03-07T12:21:33","modified_gmt":"2025-03-07T12:21:33","slug":"factory-supply-nn-bistrifluoromethylsulfonylaniline-cas-37595-74-7-with-best-price","status":"publish","type":"product","link":"https:\/\/vivalr.com\/pt\/product\/163.html","title":{"rendered":"Factory Supply N,N-bis(trifluoromethylsulfonyl)aniline CAS 37595-74-7 With Best Price"},"content":{"rendered":"<div class=\"toc\">\n<h2>\u00cdndice<\/h2>\n<ul>\n<li><a href=\"#product-info\">1. Informa\u00e7\u00f5es sobre o produto<\/a><\/li>\n<li><a href=\"#applications\">2. Aplica\u00e7\u00f5es<\/a><\/li>\n<li><a href=\"#usage\">3. Diretrizes de utiliza\u00e7\u00e3o<\/a><\/li>\n<li><a href=\"#case-studies\">4. Estudos de caso<\/a><\/li>\n<li><a href=\"#contact\">5. Contactar-nos<\/a><\/li>\n<\/ul>\n<\/div>\n<div class=\"content\">\n<h1 id=\"product-info\">N,N-bis(trifluoromethylsulfonyl)aniline (CAS 37595-74-7) User Guide<\/h1>\n<h2>1. Informa\u00e7\u00f5es sobre o produto<\/h2>\n<p><strong>Nome qu\u00edmico:<\/strong> N,N-bis(trifluoromethylsulfonyl)aniline<\/p>\n<p><strong>N\u00famero CAS:<\/strong> 37595-74-7<\/p>\n<p><strong>F\u00f3rmula molecular:<\/strong> C\u2088H\u2085F\u2086NO\u2084S\u2082<\/p>\n<p><strong>Peso molecular:<\/strong> 369.25 g\/mol<\/p>\n<p><strong>Apar\u00eancia:<\/strong> P\u00f3 cristalino branco a esbranqui\u00e7ado<\/p>\n<p><strong>Pureza:<\/strong> \u226598% (HPLC)<\/p>\n<p><strong>Armazenamento:<\/strong> Armazenar num local fresco e seco a 2-8\u00b0C sob atmosfera inerte.<\/p>\n<h2 id=\"applications\">2. Aplica\u00e7\u00f5es<\/h2>\n<p>N,N-bis(trifluoromethylsulfonyl)aniline is a high-performance <strong>electrophilic trifluoromethylation reagent<\/strong> widely used in:<\/p>\n<ul>\n<li>Organic synthesis for introducing trifluoromethyl groups into aromatic and heteroaromatic compounds.<\/li>\n<li>Pharmaceutical intermediates for drug discovery and development.<\/li>\n<li>Agrochemical production to enhance compound stability and bioactivity.<\/li>\n<li>Advanced material science for fluorinated polymer research.<\/li>\n<\/ul>\n<h2 id=\"usage\">3. Diretrizes de utiliza\u00e7\u00e3o<\/h2>\n<h3>Precau\u00e7\u00f5es de seguran\u00e7a<\/h3>\n<ul>\n<li>Usar EPI: luvas, \u00f3culos de prote\u00e7\u00e3o e bata de laborat\u00f3rio.<\/li>\n<li>Handle under nitrogen\/argon in a fume hood.<\/li>\n<\/ul>\n<h3>Typical Reaction Setup<\/h3>\n<ol>\n<li>Dissolve substrate (1 equiv) in anhydrous dichloromethane (DCM).<\/li>\n<li>Add N,N-bis(trifluoromethylsulfonyl)aniline (1.2 equiv) at 0\u00b0C.<\/li>\n<li>Stir at room temperature for 6-12 hours.<\/li>\n<li>Quench with ice water and extract with DCM.<\/li>\n<li>Purify via column chromatography (hexane:ethyl acetate = 4:1).<\/li>\n<\/ol>\n<h2 id=\"case-studies\">4. Estudos de caso<\/h2>\n<h3>Case 1: Trifluoromethylation of Indole Derivatives<\/h3>\n<p><strong>Rea\u00e7\u00e3o:<\/strong> Indole + N,N-bis(trifluoromethylsulfonyl)aniline \u2192 3-Trifluoromethylindole<\/p>\n<p><strong>Condi\u00e7\u00f5es:<\/strong> DCM, 25\u00b0C, 8 hours<\/p>\n<p><strong>Rendimento:<\/strong> 82%<\/p>\n<p><strong>Key Advantage:<\/strong> Superior regioselectivity compared to Umemoto's reagent.<\/p>\n<h3>Caso 2: S\u00edntese de um intermedi\u00e1rio farmac\u00eautico<\/h3>\n<p>Used in final-step trifluoromethylation of a COX-2 inhibitor precursor, achieving 78% yield with 99.5% HPLC purity.<\/p>\n<h2 id=\"contact\">5. Contactar-nos<\/h2>\n<p>Para quest\u00f5es t\u00e9cnicas ou encomendas por grosso:<\/p>\n<p>  <strong>Correio eletr\u00f3nico:<\/strong> <a href=\"mailto:info@vivalr.com\">info@vivalr.com<\/a><\/p>\n<p>  <strong>Telefone:<\/strong> <a href=\"tel:+8615866781826\">(86) 15866781826<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Table of Contents 1. Product Information 2. Applications 3. Usage Guidelines 4. Case Studies 5. Contact Us N,N-bis(trifluoromethylsulfonyl)aniline (CAS 37595-74-7) User Guide 1. Product Information Chemical Name: N,N-bis(trifluoromethylsulfonyl)aniline CAS Number: 37595-74-7 Molecular Formula: C\u2088H\u2085F\u2086NO\u2084S\u2082 Molecular Weight: 369.25 g\/mol Appearance: White to off-white crystalline powder Purity: \u226598% (HPLC) Storage: Store in a cool, dry place at [&hellip;]<\/p>","protected":false},"featured_media":21252,"comment_status":"closed","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[15],"product_tag":[],"class_list":{"0":"post-163","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-uncategorized","8":"first","9":"instock","10":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Factory Supply N,N-bis(trifluoromethylsulfonyl)aniline CAS 37595-74-7 With Best Price - Welcome to VIVALR- Your Trusted Source for Chemical Raw Materials\uff01<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/vivalr.com\/pt\/product\/163.html\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Factory Supply N,N-bis(trifluoromethylsulfonyl)aniline CAS 37595-74-7 With Best Price\" \/>\n<meta property=\"og:description\" content=\"Table of Contents 1. 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Product Information 2. Applications 3. Usage Guidelines 4. Case Studies 5. Contact Us N,N-bis(trifluoromethylsulfonyl)aniline (CAS 37595-74-7) User Guide 1. Product Information Chemical Name: N,N-bis(trifluoromethylsulfonyl)aniline CAS Number: 37595-74-7 Molecular Formula: C\u2088H\u2085F\u2086NO\u2084S\u2082 Molecular Weight: 369.25 g\/mol Appearance: White to off-white crystalline powder Purity: \u226598% (HPLC) Storage: Store in a cool, dry place at [&hellip;]","og_url":"https:\/\/vivalr.com\/pt\/product\/163.html","og_site_name":"Welcome to VIVALR- Your Trusted Source for Chemical Raw Materials\uff01","article_modified_time":"2025-03-07T12:21:33+00:00","og_image":[{"width":1167,"height":1177,"url":"https:\/\/vivalr.com\/wp-content\/uploads\/2025\/03\/37595-74-7.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Tempo estimado de leitura":"1 minuto"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/vivalr.com\/product\/163.html","url":"https:\/\/vivalr.com\/product\/163.html","name":"Factory Supply N,N-bis(trifluoromethylsulfonyl)aniline CAS 37595-74-7 With Best Price - Welcome to VIVALR- Your Trusted Source for Chemical Raw Materials\uff01","isPartOf":{"@id":"https:\/\/vivalr.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/vivalr.com\/product\/163.html#primaryimage"},"image":{"@id":"https:\/\/vivalr.com\/product\/163.html#primaryimage"},"thumbnailUrl":"https:\/\/vivalr.com\/wp-content\/uploads\/2025\/03\/37595-74-7.jpg","datePublished":"2025-03-07T12:05:11+00:00","dateModified":"2025-03-07T12:21:33+00:00","breadcrumb":{"@id":"https:\/\/vivalr.com\/product\/163.html#breadcrumb"},"inLanguage":"pt-PT","potentialAction":[{"@type":"ReadAction","target":["https:\/\/vivalr.com\/product\/163.html"]}]},{"@type":"ImageObject","inLanguage":"pt-PT","@id":"https:\/\/vivalr.com\/product\/163.html#primaryimage","url":"https:\/\/vivalr.com\/wp-content\/uploads\/2025\/03\/37595-74-7.jpg","contentUrl":"https:\/\/vivalr.com\/wp-content\/uploads\/2025\/03\/37595-74-7.jpg","width":1167,"height":1177},{"@type":"BreadcrumbList","@id":"https:\/\/vivalr.com\/product\/163.html#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/vivalr.com\/"},{"@type":"ListItem","position":2,"name":"Shop","item":"https:\/\/vivalr.com\/shop\/"},{"@type":"ListItem","position":3,"name":"Factory Supply N,N-bis(trifluoromethylsulfonyl)aniline CAS 37595-74-7 With Best Price"}]},{"@type":"WebSite","@id":"https:\/\/vivalr.com\/#website","url":"https:\/\/vivalr.com\/","name":"Bem-vindo ao VIVALR- Sua fonte confi\u00e1vel de mat\u00e9rias-primas qu\u00edmicas\uff01","description":"Descubra uma vasta gama de mat\u00e9rias-primas qu\u00edmicas de alta qualidade para satisfazer as suas necessidades industriais. 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