2-Pyrrolidinone CAS 616-45-5： Everything You Need to Know About This Compound

Abstract

This article provides an in-depth overview of 2-Pyrrolidinone, a compound with the CAS number 616-45-5. It explores its chemical properties, synthesis methods, applications in various industries, safety considerations, and environmental impact. By delving into these aspects, the article aims to offer a comprehensive understanding of this compound and its significance in modern chemistry and industry.

Introduction to 2-Pyrrolidinone CAS 616-45-5

2-Pyrrolidinone, also known as N-vinyl-2-pyrrolidone, is a cyclic amide derivative that finds extensive use in various industrial applications. With the CAS number 616-45-5, it is a colorless, volatile liquid that is soluble in water and organic solvents. This compound is primarily used as a monomer for the production of polyvinylpyrrolidone (PVP), a polymer with a wide range of applications in pharmaceuticals, cosmetics, and adhesives.

Chemical Properties of 2-Pyrrolidinone

2-Pyrrolidinone has a molecular formula of C4H7NO and a molecular weight of 73.09 g/mol. It features a five-membered ring structure with a nitrogen atom and a double bond. The compound is characterized by its high boiling point of 247°C and a melting point of -25°C. Its solubility in water is relatively low, but it is highly soluble in organic solvents such as acetone, alcohol, and ether. These properties make it suitable for various applications where its chemical stability and solubility are crucial.

Synthesis of 2-Pyrrolidinone

The synthesis of 2-pyrrolidinone can be achieved through several methods, including the condensation of α,β-unsaturated aldehydes with amines, the cyclization of α,β-unsaturated esters, and the hydrolysis of N-vinylcarbamates. The most common industrial method involves the reaction of ethylene oxide with ethylamine, which yields 2-pyrrolidinone as a byproduct. This process is highly efficient and cost-effective, making it the preferred method for large-scale production.

Applications of 2-Pyrrolidinone

2-Pyrrolidinone serves as a key monomer in the production of polyvinylpyrrolidone (PVP), which is a versatile polymer used in numerous applications. PVP is used in pharmaceuticals as a suspending agent, stabilizer, and binder. In cosmetics, it acts as a thickener, emulsifier, and skin protectant. Additionally, PVP finds use in adhesives, coatings, and textiles, where its adhesive properties and water resistance are beneficial.

Safety Considerations

While 2-pyrrolidinone is widely used in various industries, it is important to consider its safety profile. The compound is classified as a hazardous substance due to its potential to cause irritation to the eyes, skin, and respiratory system. Proper handling and storage are essential to minimize exposure risks. Workers handling 2-pyrrolidinone should wear appropriate personal protective equipment, such as gloves, goggles, and respirators, to prevent accidental contact.

Environmental Impact

The environmental impact of 2-pyrrolidinone and its derivatives, such as PVP, is a subject of concern. The compound is biodegradable, but its breakdown products can still be harmful to aquatic life. Additionally, the production and disposal of PVP can lead to environmental contamination. Efforts are being made to develop more sustainable and environmentally friendly alternatives to reduce the ecological footprint of these compounds.

Conclusion

In conclusion, 2-Pyrrolidinone CAS 616-45-5 is a versatile compound with significant applications in various industries. Its chemical properties, synthesis methods, and safety considerations are crucial factors to understand when working with this compound. While it offers numerous benefits, it is essential to address its environmental impact and strive for sustainable practices. By doing so, we can ensure the safe and responsible use of 2-pyrrolidinone and its derivatives in the future.

Keywords

2-Pyrrolidinone, CAS 616-45-5, chemical properties, synthesis, applications, safety, environmental impact, polyvinylpyrrolidone (PVP), hazardous substance.