The product Factory Supply 1.1′-binaphthyl-2.2′-diphemyl phosphine cas 98327-87-8 is a high - quality chemical compound offered at the best price. Its CAS number 98327 - 87 - 8 uniquely identifies it in the chemical industry. This compound belongs to the family of organophosphorus compounds and has a specific molecular structure based on the binaphthyl and diphenyl phosphine groups.
Regarding its physical and chemical properties, it has a certain melting point, boiling point, and solubility characteristics that make it suitable for various applications. The purity of the product is carefully controlled during the factory supply process to ensure consistent quality for end - users.
1.1′-binaphthyl-2.2′-diphemyl phosphine is widely used in the field of organic synthesis. It serves as a chiral ligand in asymmetric catalysis reactions. Asymmetric catalysis is a crucial process in the production of enantiomerically pure compounds, which are essential in the pharmaceutical, agrochemical, and fine - chemical industries. By using this compound as a ligand, chemists can control the stereochemistry of a reaction and obtain the desired chiral product with high enantiomeric excess.
It can also be used in the preparation of advanced materials. Some electronic and optical materials require specific chemical structures for their unique properties, and this phosphine compound can be incorporated into these materials during the synthesis process to modify their performance.
When using 1.1′-binaphthyl-2.2′-diphemyl phosphine, it is important to follow proper laboratory safety procedures. Wear appropriate personal protective equipment, such as gloves and goggles, to avoid direct contact with the compound. Since it is often used in organic synthesis, it should be stored in a dry and cool place, away from sources of heat and ignition.
In an asymmetric catalysis reaction, the compound is typically dissolved in a suitable organic solvent, such as toluene or dichloromethane. The amount of the phosphine ligand used depends on the specific reaction conditions and the nature of the substrate. Usually, a catalytic amount (a small fraction compared to the substrate) is sufficient to promote the reaction. After adding the ligand to the reaction mixture, other reactants and catalysts can be added in a sequential manner, and the reaction is carried out under optimized temperature and pressure conditions.
Case 1: Pharmaceutical synthesis
In the synthesis of a new anti - cancer drug, a pharmaceutical company used 1.1′-binaphthyl-2.2′-diphemyl phosphine as a chiral ligand in an asymmetric hydrogenation reaction. The target molecule had a chiral center, and obtaining the correct enantiomer was crucial for its biological activity. By using this phosphine ligand, the reaction achieved an enantiomeric excess of over 90%. This high selectivity reduced the amount of unwanted by - products and simplified the purification process, ultimately leading to an efficient and cost - effective synthesis of the drug.
Case 2: Agrochemical production
An agrochemical manufacturer needed to synthesize a chiral pesticides. The use of 1.1′-binaphthyl-2.2′-diphemyl phosphine in an asymmetric allylation reaction provided a way to control the stereochemistry of the product. The resulting chiral pesticide had enhanced biological activity against pests compared to its racemic mixture, and the use of this phosphine ligand in the synthesis process improved the overall quality and effectiveness of the agrochemical product.
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