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DL-4-Chlorophenylglycine (CAS 6212-33-5) User Guide: Uses, Applications, and Best Practices

Table of Contents

1. Product Overview

DL-4-Chlorophenylglycine (CAS 6212-33-5) is a high-purity organic compound supplied as a white to off-white crystalline powder. Key specifications include:

  • Chemical Name: DL-4-Chlorophenylglycine
  • CAS Number: 6212-33-5
  • Molecular Formula: C8H8ClNO2
  • Molecular Weight: 185.61 g/mol
  • Purity: ≥98% (HPLC)
  • Storage: Keep in a cool, dry place at 2-8°C

2. Key Applications

DL-4-Chlorophenylglycine is widely used in:

  • Pharmaceuticals: As an intermediate in synthesizing antibiotics, antivirals, and anti-inflammatory drugs.
  • Chemical Research: For chiral resolution studies and asymmetric catalysis.
  • Agrochemicals: In the production of herbicides and fungicides.

3. Usage Instructions

  • Safety: Wear PPE (gloves, goggles, lab coat) to avoid inhalation or skin contact.
  • Solubility: Soluble in DMSO, methanol, and ethyl acetate; insoluble in water.
  • Storage: Store in airtight containers under inert gas (N2 or Ar) to prevent degradation.
  • Handling: Use under fume hood with proper ventilation.

4. Detailed Use Cases

Case 1: Synthesis of β-Lactam Antibiotics

DL-4-Chlorophenylglycine serves as a precursor in the synthesis of β-lactam antibiotics. Researchers dissolve 5g of the compound in 50ml DMSO, followed by coupling with penicillin intermediates at 40°C for 6 hours, achieving a 92% yield.

Case 2: Catalytic Asymmetric Reactions

In chiral catalysis, 0.1mmol of DL-4-Chlorophenylglycine is combined with transition metal catalysts (e.g., Ru or Pd) to achieve >90% enantiomeric excess in asymmetric hydrogenation reactions.

5. Contact Information

For technical inquiries or bulk orders:

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Vivalr, a paragon of innovation in the chemical sector, fuses cutting - edge R & D with unwavering commitment to quality. Our product spectrum, from industrial stalwarts to fine - tuned chemicals, is a testament to our versatility.

Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
2000 square R&D center
More than 20 research and development personnel,
12 sets of research and development equipment, 10 fume hoods and 6 university laboratories have been developed in cooperation
18 patents, 140 sets of chemical synthesis processes

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
For the United States, Australia, Japan, South Korea, Sweden, France, Spain and other global more than 2000 customers to provide high-quality products and services, has won the recognition and trust of customers in the industry.

More than 12 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

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By Sea, usual and economy.

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Can additional test indicators be added?

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Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Vivalr’s delivery rate is guaranteed to be 99.99%

2000+

square meter R&D center

12+

China(set) of R&D equipment

10+

Fume hood

20+

R&D team

User’evaluation of us

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