Unlock the Secrets of O-phenanthroline CAS 66-71-7： A Comprehensive Guide

Abstract

This article provides a comprehensive guide to O-phenanthroline CAS 66-71-7, a versatile chemical compound with significant applications in various fields. The guide delves into the chemical properties, synthesis methods, analytical techniques, biological roles, industrial applications, and safety considerations of O-phenanthroline. By exploring these aspects, the article aims to unlock the secrets behind this compound, offering valuable insights for researchers, scientists, and professionals in related industries.

Introduction to O-phenanthroline CAS 66-71-7

O-phenanthroline, also known as 1,10-phenanthroline, is a cyclic organic compound with the chemical formula C12H8N2. It is a derivative of phenanthroline, characterized by two nitrogen atoms in the 1,10-positions of the phenanthroline ring. O-phenanthroline is widely used in various applications due to its unique chemical properties, including its ability to form stable complexes with metal ions. This guide aims to provide a detailed overview of O-phenanthroline, covering its synthesis, analysis, biological roles, and industrial applications.

Chemical Properties of O-phenanthroline

O-phenanthroline is a yellow crystalline solid that is sparingly soluble in water but readily soluble in organic solvents such as acetone and ethanol. It has a melting point of approximately 200°C and a boiling point of around 300°C. The compound is highly reactive and can form coordination complexes with a wide range of metal ions, including iron, copper, zinc, and cobalt. These complexes are often used in analytical chemistry for the determination of metal ion concentrations.

Synthesis of O-phenanthroline

The synthesis of O-phenanthroline can be achieved through various methods, including the condensation of 1,8-diaminonaphthalene with formaldehyde in the presence of an acid catalyst. Another common synthesis method involves the reaction of 1,10-phenanthroline with sodium hydroxide to form the corresponding sodium salt, which can then be converted back to the free acid form. The choice of synthesis method depends on the desired purity and scale of production.

Analysis of O-phenanthroline

The analysis of O-phenanthroline involves various techniques, including spectrophotometry, chromatography, and titrimetry. Spectrophotometric methods, such as UV-Vis spectroscopy, are commonly used for the determination of O-phenanthroline in complex matrices. Chromatographic techniques, such as high-performance liquid chromatography (HPLC), are employed for the separation and quantification of O-phenanthroline in mixtures. Titrimetric methods, such as complexometric titration, are also used for the determination of metal ion concentrations in the presence of O-phenanthroline.

Biological Roles of O-phenanthroline

O-phenanthroline has been found to have various biological roles, including its use as a chelating agent in the treatment of heavy metal poisoning. It can bind to metal ions in the body, facilitating their excretion. Additionally, O-phenanthroline has been studied for its potential in cancer therapy, where it is believed to inhibit the growth of cancer cells by disrupting metalloenzymes involved in cell proliferation.

Industrial Applications of O-phenanthroline

O-phenanthroline finds extensive use in various industrial applications. It is a key component in the production of metal chelating agents, which are used in water treatment to prevent scale formation and corrosion. O-phenanthroline is also used in the pharmaceutical industry for the synthesis of drugs and as a stabilizer in food and cosmetics. Furthermore, it is employed in the electronics industry for the production of printed circuit boards and in the manufacturing of batteries.

Conclusion

In conclusion, O-phenanthroline CAS 66-71-7 is a versatile chemical compound with a wide range of applications. This comprehensive guide has explored the chemical properties, synthesis methods, analytical techniques, biological roles, and industrial applications of O-phenanthroline. By understanding these aspects, researchers, scientists, and professionals can unlock the secrets behind this compound, leading to its effective utilization in various fields.

Keywords: O-phenanthroline, CAS 66-71-7, chemical properties, synthesis, analysis, biological roles, industrial applications