Unlock the Secrets of 2-Anilinoethanol (CAS 122-98-5)： A Comprehensive Guide

Abstract

This article provides a comprehensive guide to 2-Anilinoethanol (CAS 122-98-5), a chemical compound with significant applications in various industries. The guide delves into the properties, synthesis, uses, safety considerations, and regulatory aspects of this compound. By exploring these aspects, the article aims to unlock the secrets of 2-Anilinoethanol, offering valuable insights for researchers, chemists, and industry professionals.

Introduction to 2-Anilinoethanol (CAS 122-98-5)

2-Anilinoethanol, also known as N-ethylaniline, is a chemical compound with the molecular formula C8H11N. It is a colorless to pale yellow liquid with a characteristic odor. This compound is widely used in the synthesis of dyes, pharmaceuticals, and agrochemicals. The CAS number 122-98-5 is a unique identifier for this compound, which is crucial for its identification and regulation.

Properties of 2-Anilinoethanol

2-Anilinoethanol possesses several physical and chemical properties that make it a versatile compound. It has a melting point of approximately 9-10°C and a boiling point of around 244-245°C. The compound is soluble in water, alcohol, and ether, which makes it easy to handle and process. Additionally, 2-Anilinoethanol is a weak base, with a pKa value of around 9.3, which is important for its reactivity in various chemical reactions.

Synthesis of 2-Anilinoethanol

The synthesis of 2-Anilinoethanol can be achieved through several methods, including the reaction of aniline with ethylene oxide, the reaction of aniline with ethyl halide, and the reaction of aniline with ethylamine. Each method has its own advantages and limitations, and the choice of synthesis route depends on the desired purity, yield, and cost-effectiveness. The reaction conditions, such as temperature, pressure, and catalysts, play a crucial role in the synthesis process.

Uses of 2-Anilinoethanol

2-Anilinoethanol finds extensive applications in various industries. It is a key intermediate in the synthesis of dyes, particularly in the production of azo dyes, which are widely used in textiles, plastics, and leather industries. In the pharmaceutical industry, 2-Anilinoethanol is used as a starting material for the synthesis of several drugs, including analgesics and anti-inflammatory agents. Moreover, it is also employed in the agrochemical sector for the production of herbicides and insecticides.

Safety Considerations

Handling 2-Anilinoethanol requires careful consideration of its safety profile. The compound is toxic if ingested, inhaled, or absorbed through the skin. It can cause irritation to the eyes, skin, and respiratory system. Therefore, appropriate personal protective equipment (PPE) should be worn when handling this compound. Adequate ventilation and spill containment measures are also essential to minimize the risk of exposure.

Regulatory Aspects

2-Anilinoethanol is subject to various regulations and standards, which vary by country and region. These regulations are in place to ensure the safe and responsible use of the compound. The European Chemicals Agency (ECHA) and the United States Environmental Protection Agency (EPA) are among the regulatory bodies that oversee the use and handling of 2-Anilinoethanol. Compliance with these regulations is crucial for manufacturers, distributors, and users of the compound.

Conclusion

In conclusion, 2-Anilinoethanol (CAS 122-98-5) is a versatile chemical compound with significant applications in various industries. This comprehensive guide has explored the properties, synthesis, uses, safety considerations, and regulatory aspects of this compound. By understanding these aspects, researchers, chemists, and industry professionals can unlock the secrets of 2-Anilinoethanol and utilize its potential to the fullest.

Keywords: 2-Anilinoethanol, CAS 122-98-5, chemical properties, synthesis, uses, safety, regulatory aspects