Tween 60, with the CAS number 9005 - 67 - 8, is a non - ionic surfactant. It appears as a yellow to amber viscous liquid or semi - solid at room temperature. This product is known for its high quality and is offered at the best price in the market. The chemical name of Tween 60 is Polyoxyethylene (20) Sorbitan Monostearate. It has a HLB (Hydrophilic - Lipophilic Balance) value of approximately 14.9, which indicates its good emulsifying and dispersing properties. The density of Tween 60 is around 1.08 g/cm³, and its solubility shows that it is soluble in water, ethanol, and other organic solvents.
Tween 60 has a wide range of applications across various industries. In the food industry, it is used as an emulsifier, stabilizer, and dispersant. It can prevent oil and water from separating in food products such as ice creams, salad dressings, and margarines, thus improving the texture and shelf - life of these products. In the pharmaceutical field, Tween 60 is utilized as a solubilizer and emulsifier in oral, topical, and parenteral formulations. It can enhance the bioavailability of poorly soluble drugs by forming micelles. In the cosmetic industry, it is added to creams, lotions, and shampoos as an emulsifying agent to create a smooth and stable product. Moreover, in the textile industry, Tween 60 is used as a wetting agent and emulsifier in dyeing and finishing processes, which helps to improve the dyeing effect and the overall quality of the textiles.
When using Tween 60, it is important to follow the appropriate procedures. In food applications, the dosage usually ranges from 0.1% to 1% depending on the type of food product. First, dissolve Tween 60 in a small amount of warm water before adding it to the food mixture. Stir thoroughly to ensure uniform dispersion. In pharmaceutical formulations, the concentration of Tween 60 can vary from 0.5% to 5%, depending on the solubility requirements of the drug. It should be added during the preparation process under controlled temperature and pH conditions. In cosmetic products, Tween 60 is typically added to the oil phase of the formulation and then emulsified with the water phase using a high - shear mixer. For textile applications, it can be added directly to the dye bath or finishing solution at a concentration of 0.5 - 2 g/L.
Case 1: Ice Cream Production
A well - known ice cream manufacturer was facing the problem of ice crystal formation and poor texture in their products. After adding Tween 60 at a concentration of 0.3% to their ice cream formula, they observed a significant improvement. The ice cream became smoother, creamier, and more resistant to melting. The emulsifying property of Tween 60 helped to disperse the fat globules evenly, preventing them from coalescing and forming large ice crystals.
Case 2: Pharmaceutical Tablet Coating
A pharmaceutical company was developing a new tablet formulation with a poorly soluble drug. By using Tween 60 as a solubilizer in the tablet coating at a concentration of 1%, they were able to improve the drug's dissolution rate. The bioavailability of the drug increased, leading to better therapeutic effects.
Case 3: Cosmetic Lotion
A cosmetic brand was struggling to create a stable lotion with a high oil content. They added Tween 60 to the oil phase at a concentration of 2% and emulsified it with the water phase. The resulting lotion had a smooth and consistent texture, and there was no separation of the oil and water phases even after several months of storage.
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