Rifamycin S is a well - known antibiotic compound, identified by the CAS number 13553 - 79 - 2. It belongs to the rifamycin class of antibiotics. Rifamycin S is a red - colored compound that is soluble in organic solvents such as methanol, ethanol, and acetone but has limited solubility in water. It has a molecular formula of C₃₇H₄₅NO₁₂ and a molecular weight of approximately 699.75 g/mol. The high - quality Rifamycin S we offer is synthesized under strict quality control standards, ensuring its purity and effectiveness.
Medical Field: Rifamycin S is primarily used in the medical field as an antibacterial agent. It has a broad - spectrum activity against many Gram - positive and some Gram - negative bacteria. It is especially effective against mycobacteria, including the bacteria that cause tuberculosis. In combination with other antibiotics, it can be used to treat severe bacterial infections, reducing the risk of antibiotic resistance.
Research Purposes: In scientific research, Rifamycin S is an important tool. It can be used to study the mechanism of bacterial RNA synthesis. By inhibiting RNA polymerase in bacteria, it helps researchers understand the essential biological processes in bacteria, which is crucial for developing new antibiotics and antibacterial strategies.
Medical Use: When used in medical treatment, Rifamycin S should be administered under the supervision of a qualified healthcare professional. It can be formulated into oral tablets, injections, or other dosage forms. The dosage depends on the type and severity of the infection, the patient's age, weight, and overall health condition.
Research Use: In a laboratory setting, Rifamycin S is usually dissolved in an appropriate organic solvent to prepare a stock solution. The concentration of the stock solution can vary according to the specific experimental requirements. When conducting experiments, appropriate volumes of the stock solution are added to the culture media to achieve the desired final concentration.
Medical Case: A patient with a severe staphylococcal infection was treated with a combination of Rifamycin S and another antibiotic. Before treatment, the patient had high fever, local inflammation, and systemic symptoms. After a two - week treatment course, the patient's symptoms significantly improved. The fever subsided, and the local inflammation gradually disappeared. Follow - up tests showed a significant reduction in the number of bacteria in the patient's body, indicating the effectiveness of Rifamycin S in treating this type of infection.
Research Case: A research team was studying the mechanism of antibiotic resistance in mycobacteria. They used Rifamycin S to inhibit RNA polymerase in the mycobacterial cultures. By analyzing the changes in gene expression and bacterial growth, they discovered a new mechanism of antibiotic resistance related to the mutation of the RNA polymerase gene. This finding provides new insights into the development of new drugs to combat antibiotic - resistant mycobacteria.
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