1. Product Overview

2,2′-Biphenol (CAS 1806-29-7) is a high-purity organic compound with the following specifications:

• Chemical Formula: C₁₂H₁₀O₂
• Molecular Weight: 186.21 g/mol
• Appearance: White to off-white crystalline powder
• Melting Point: 145-148°C
• Purity: ≥99% (HPLC)
• Storage: Keep in a cool, dry place away from light; store in sealed containers.

2. Key Applications

2,2′-Biphenol is widely used in:

• Organic Synthesis: As a ligand or catalyst in cross-coupling reactions.
• Pharmaceuticals: Intermediate for antiviral and anticancer agents.
• Polymer Industry: Antioxidant and stabilizer for polymers.
• Electronics: Precursor for liquid crystals and optoelectronic materials.

3. Usage Guidelines

• Safety Precautions: Wear PPE (gloves, goggles) to avoid inhalation or skin contact.
• Handling: Use under inert atmosphere (e.g., N₂) to prevent oxidation.
• Solubility: Dissolve in ethanol, THF, or DCM; stir at 25-50°C for optimal results.
• Storage: Maintain temperature below 25°C; reseal containers immediately after use.

4. Practical Use Cases

Case 1: Suzuki-Miyaura Cross-Coupling Reaction

Step-by-Step:

1. Mix 2,2′-Biphenol (0.1 mmol) with Pd(OAc)₂ in anhydrous THF.
2. Add aryl halide (1.2 eq) and boronic acid (1.5 eq) under N₂.
3. Heat at 80°C for 12 hours; yield reaches 92% with 99% selectivity.

Case 2: Polymer Stabilization

Process: Add 0.5% w/w 2,2′-Biphenol to polypropylene during extrusion. Reduces thermal degradation by 70% at 200°C.