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Estimated delivery time: 3-5 days

Butyltriphenylphosphonium Chloride (CAS 13371-17-0) User Guide: Applications, Usage, and Case Studies

1. Product Overview

Butyltriphenylphosphonium Chloride (CAS 13371-17-0) is a quaternary phosphonium salt widely used in organic synthesis. Key specifications include:

Chemical Formula: C₂₃H₂₆ClP
Molecular Weight: 368.87 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage: Keep in a cool, dry place at 2-8°C

2. Key Applications

Butyltriphenylphosphonium Chloride serves as a versatile reagent in:

Phase-transfer catalysis for alkylation and acylation reactions
Stabilizing ylides in Wittig reactions
Facilitating nucleophilic substitutions in organic synthesis
Promoting esterification and transesterification processes

3. Usage Instructions

Wear PPE (gloves, goggles, lab coat) when handling
Dissolve in polar aprotic solvents (e.g., DMF, DMSO) before use
Use at 0.5-2.0 mol% concentration relative to substrate
Maintain reaction temperatures between 20-80°C
Quench reactions with aqueous solutions for easy separation

4. Practical Case Studies

Case 1: Synthesis of Quaternary Ammonium Salts

In a typical alkylation reaction:

Mix 1.0g Butyltriphenylphosphonium Chloride with 50ml DMF
Add 5mmol primary amine and 5.5mmol alkyl bromide
Heat at 60°C for 4 hours under nitrogen
Yield: 92% quaternary ammonium salt after purification

Case 2: Wittig Reaction Optimization

For olefin synthesis:

Combine 2mol% catalyst with aldehyde substrate
Generate ylide at room temperature for 30 minutes
React with alkene precursor at 40°C for 2 hours
Achieve 85% conversion rate with E-selectivity >90%

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Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
2000 square R&D center
More than 20 research and development personnel,
12 sets of research and development equipment, 10 fume hoods and 6 university laboratories have been developed in cooperation
18 patents, 140 sets of chemical synthesis processes

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
For the United States, Australia, Japan, South Korea, Sweden, France, Spain and other global more than 2000 customers to provide high-quality products and services, has won the recognition and trust of customers in the industry.

More than 12 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

Mode of Transportation

By Air, fast but expensive.

By Sea, usual and economy.

By Train, suit for middle Asia countries.

FAQ

Does it support auditing?

Environmental Protection Science and Technology Park, Zhengfeng Road, High-tech Zone, Jinan City, Shandong Province

Whether to provide samples?

Free samples can be provided, and customers only need to pay the corresponding shipping costs

Delivery time

There are stock in the warehouse, and some products need to be customized for production within 3 working days, depending on the workshop situation and production schedule

What payment methods and currencies are accepted here?

We accept payment methods such as TT, Western Union, and letter of credit, etc. Meanwhile, we support currencies like US dollars, euros, RMB, and Bitcoin, etc.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Vivalr’s delivery rate is guaranteed to be 99.99%

2000+

square meter R&D center

12+

China(set) of R&D equipment

10+

Fume hood

20+

R&D team

User’evaluation of us

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