Pyrrolo[1,2-f][1,2,4]triazin-4-amine (CAS 159326-68-8) is a high-purity heterocyclic compound with the following specifications:
This compound is widely used in:
Used as core scaffold in JAK3 kinase inhibitor development (0.5 mol% loading, 72% yield). Demonstrated IC₅₀ of 12 nM in cellular assays.
Derivatized into novel quinolone hybrids showing 8x improved activity against Gram-positive pathogens compared to baseline compounds.
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