High Quality 3-HYDROXY-2,4,6-TRIIODOBENZOIC ACID CAS 53279-72-4: User Guide

1. Product Information

3-HYDROXY-2,4,6-TRIIODOBENZOIC ACID (CAS 53279-72-4) is a high-purity iodinated aromatic compound widely used in pharmaceutical and chemical research. Key specifications include:

• Chemical Formula: C₇H₃I₃O₃
• Molecular Weight: 499.81 g/mol
• Appearance: Off-white to pale yellow crystalline powder
• Purity: ≥98% (HPLC)
• Solubility: Soluble in alkaline solutions, DMSO, and DMF
• Storage: Store in a cool, dry place away from light at 2-8°C

2. Product Usage

This compound serves critical roles in:

• X-ray Contrast Media: Intermediate for iodinated contrast agents in medical imaging.
• Organic Synthesis: Building block for pharmaceuticals and specialty chemicals.
• Research Applications: Used in studying iodine-containing compounds’ biochemical behavior.

3. Product Application

Handling Guidelines:

• Wear PPE (gloves, goggles, lab coat) to avoid direct contact.
• Dissolve in alkaline buffers (pH 8-10) for optimal solubility.
• Use under fume hood for large-scale reactions.

Storage Tips: Keep container tightly sealed under inert gas (argon/nitrogen) to prevent degradation.

4. Detailed Use Cases

Case 1: X-ray Contrast Agent Synthesis

Used as a precursor in synthesizing iopamidol, a non-ionic contrast agent for CT scans. Reaction steps involve iodination and hydroxyl group protection, achieving >90% yield under controlled conditions.

Case 2: Antithyroid Drug Intermediate

Key intermediate in producing methimazole analogs. Reacts with thiourea derivatives to form thioamide bonds, enabling iodine-controlled release mechanisms.

Case 3: Radiolabeling Studies

Employed in ¹²⁵I radiolabeling experiments for tracking drug metabolism in preclinical models, with 85% radiochemical purity post-purification.

5. Contact Information

For technical inquiries or bulk orders:

• Email: info@vivalr.com
• Phone: (86) 15866781826