2-Ethylbutyryl Chloride (CAS 2736-40-5) is a high-purity organic compound with the molecular formula C6H11ClO and a molecular weight of 134.6 g/mol. This colorless to pale yellow liquid has a boiling point of 150-152°C (760 mmHg) and a density of 1.02 g/cm3. It is stored under inert gas (nitrogen) at 2-8°C to ensure stability.
This compound is widely used as an acylating agent in:
Safety Precautions:
Steps:
Case 1: Pharmaceutical Synthesis
In the production of antibiotic intermediates, 2-Ethylbutyryl Chloride (5 mmol) reacts with aminophenol derivatives in dichloromethane at 0°C. After stirring for 2 hours, the acylated product is isolated in 85% yield for further purification.
Case 2: Agrochemical Manufacturing
Used to synthesize herbicide precursors by reacting with thiourea derivatives in toluene under reflux. The reaction achieves 92% conversion, enabling efficient large-scale production.
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