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1,5-Naphthalenedisulfonic Acid (CAS 81-04-9) User Guide: Applications, Usage & Case Studies

Table of Contents

1. Product Overview

1,5-Naphthalenedisulfonic Acid (CAS 81-04-9) is a sulfonic acid derivative with the molecular formula C10H8O6S2. Key specifications include:

  • Molecular Weight: 288.3 g/mol
  • Appearance: White to off-white crystalline powder
  • Solubility: Soluble in water and alkaline solutions
  • Storage: Store in a cool, dry place away from light and moisture

2. Key Applications

1,5-Naphthalenedisulfonic acid serves as a versatile intermediate in:

  • Dye & Pigment Industry: Synthesis of azo dyes and optical brighteners
  • Pharmaceuticals: Precursor for active pharmaceutical ingredients (APIs)
  • Water Treatment: Chelating agent for metal ion removal
  • Electroplating: Additive for surface finishing processes

3. Usage Instructions

Safety Precautions:

  • Wear PPE (gloves, goggles, lab coat)
  • Avoid inhalation or direct skin contact

Processing Guidelines:

  1. Dissolve in alkaline solutions (pH 8-10) at 40-60°C
  2. Use stoichiometric ratios per reaction requirements
  3. Neutralize residuals before disposal

4. Practical Case Studies

Case 1: Dye Intermediate Synthesis

A textile manufacturer used 1,5-NDSA (2.5 kg) reacted with aniline derivatives to produce a high-yield (92%) azo dye batch, achieving superior color fastness.

Case 2: Pharmaceutical Intermediate

In API production, 1,5-NDSA was sulfonated under controlled conditions (80°C, 4 hrs) to synthesize a hypertension drug precursor with 98.5% purity.

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About the company

Vivalr, a paragon of innovation in the chemical sector, fuses cutting - edge R & D with unwavering commitment to quality. Our product spectrum, from industrial stalwarts to fine - tuned chemicals, is a testament to our versatility.

Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
2000 square R&D center
More than 20 research and development personnel,
12 sets of research and development equipment, 10 fume hoods and 6 university laboratories have been developed in cooperation
18 patents, 140 sets of chemical synthesis processes

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
For the United States, Australia, Japan, South Korea, Sweden, France, Spain and other global more than 2000 customers to provide high-quality products and services, has won the recognition and trust of customers in the industry.

More than 12 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

Mode of Transportation

By Air, fast but expensive.

By Sea, usual and economy.

By Train, suit for middle Asia countries.

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Does it support auditing?

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Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Vivalr’s delivery rate is guaranteed to be 99.99%

2000+

square meter R&D center

12+

China(set) of R&D equipment

10+

Fume hood

20+

R&D team

User’evaluation of us

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Marcus Long

" In years of sourcing from China, first found working with Sincere Chemical great. They help in production, delivery and tech, saving time. When first asking Zhai for optical brightener quote, got detailed one with prices, trade details, company info, R&D and production capacity, packaging and raw material control."

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Emma Kung

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