m-Tolualdehyde CAS 620-23-5: Comprehensive User Guide
Table of Contents
1. Product Overview
m-Tolualdehyde (CAS 620-23-5) is an organic compound with the molecular formula C8H8O. Key specifications include:
- Appearance: Clear to pale yellow liquid
- Molecular Weight: 120.15 g/mol
- Purity: ≥98%
- Boiling Point: 199-201°C
- Density: 1.019 g/cm³
- Storage: Keep in a cool, dry place away from light and oxidizers
2. Applications of m-Tolualdehyde
m-Tolualdehyde is widely used as a chemical intermediate in:
- Pharmaceutical synthesis (e.g., antihistamines and antifungal agents)
- Flavor and fragrance manufacturing
- Agrochemical production (pesticides and herbicides)
- Dye and resin manufacturing
3. Usage Instructions
- Safety Precautions: Wear PPE (gloves, goggles, lab coat) and work in a well-ventilated area.
- Handling: Avoid direct contact with skin or eyes. Use corrosion-resistant equipment.
- Reaction Conditions: Typically used in catalytic reactions at 50-80°C under inert atmospheres.
- Storage: Store in sealed containers with nitrogen padding to prevent oxidation.
4. Detailed Use Cases
Case 1: Pharmaceutical Intermediate Synthesis
Used to produce Loratadine (antihistamine) via reductive amination. Process involves reacting m-Tolualdehyde with ethylenediamine derivative under hydrogenation conditions.
Case 2: Perfume Ingredient Production
Key precursor for musk fragrances. Converted to meta-tolyl aldehyde dimethyl acetal through acid-catalyzed reactions with methanol.
Case 3: Agricultural Chemical Formulation
Intermediate in synthesis of pyrethroid insecticides. Reacted with cyclopropane derivatives to enhance pesticidal activity.
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