Chemical Name: Borodimethylglycine
CAS Number: 77356-05-9
Molecular Formula: C4H8BNO2
Molecular Weight: 112.92 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC grade)
Storage: Store in a cool, dry place at 2-8°C
Used as a key intermediate in the production of boron-containing kinase inhibitors. Researchers achieved 72% yield improvement through optimized stoichiometry (1:1.2 ratio with substrate).
Demonstrated 89% efficiency in cross-coupling reactions when used at 0.5 mol% loading. Reaction time reduced from 24h to 6h under mild conditions (60°C, atmospheric pressure).
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