Calix[4]arene, with the CAS number 74568-07-3, is a macrocyclic compound that belongs to the calixarene family. Our product is of high - quality and is offered at a low price.
The molecular formula of Calix[4]arene is (C_{28}H_{24}O_4), and its molecular weight is approximately 424.49 g/mol. It typically appears as a white to off - white crystalline powder. The purity of our product can reach up to 98% or higher, which ensures its excellent performance in various applications. It has a melting point in the range of 310 - 314°C. The compound is relatively stable under normal storage conditions but should be protected from light, heat, and moisture.
Calix[4]arene has a wide range of applications in different fields:
1. Supramolecular Chemistry: It serves as a host molecule in supramolecular chemistry. It can form inclusion complexes with various guest molecules through non - covalent interactions such as hydrogen bonding, van der Waals forces, and hydrophobic interactions. These complexes have potential applications in molecular recognition, sensors, and drug delivery systems.
2. Analytical Chemistry: Calix[4]arene can be used as a ligand for the extraction and separation of metal ions. It has a high selectivity for certain metal ions, which makes it useful in analytical techniques such as solid - phase extraction and ion - exchange chromatography.
3. Organic Synthesis: It can act as a catalyst or a template in organic synthesis reactions. For example, it can promote the formation of specific chemical bonds or control the stereochemistry of reaction products.
1. Storage: Store the product in a cool, dry place away from direct sunlight. Keep the container tightly closed to prevent moisture absorption and contamination.
2. Handling: When handling Calix[4]arene, wear appropriate personal protective equipment, including gloves and safety goggles. Avoid inhalation of dust and direct skin contact. In case of contact, immediately wash the affected area with plenty of water.
3. Dissolution: For most applications, Calix[4]arene can be dissolved in common organic solvents such as chloroform, dichloromethane, and toluene. The solubility may vary depending on the solvent and temperature. To dissolve the compound, add a suitable amount of solvent to the sample and stir gently until completely dissolved.
4. Reaction Conditions: When using Calix[4]arene in chemical reactions, optimize the reaction conditions such as temperature, reaction time, and the molar ratio of reactants according to the specific reaction requirements.
Case 1: Metal Ion Extraction in Environmental Analysis
In an environmental research project, Calix[4]arene was used to extract lead ions ((Pb^{2 +})) from water samples. A solid - phase extraction column was prepared by packing Calix[4]arene - functionalized silica gel. The water samples were passed through the column, and the lead ions were selectively retained on the column due to the strong interaction with Calix[4]arene. After washing the column with a suitable buffer solution to remove impurities, the lead ions were eluted with an acidic solution. The eluted lead ions were then analyzed by atomic absorption spectrometry. The results showed that Calix[4]arene had a high extraction efficiency for lead ions, with a recovery rate of over 90%.
Case 2: Supramolecular Sensor for Glucose Detection
Researchers developed a supramolecular sensor based on Calix[4]arene for glucose detection. Calix[4]arene was modified with fluorescent groups. When glucose molecules were present in the solution, they formed inclusion complexes with Calix[4]arene, which led to a change in the fluorescence intensity of the system. By measuring the fluorescence intensity, the concentration of glucose in the solution could be determined. This sensor showed high selectivity and sensitivity for glucose detection, and it has potential applications in medical diagnosis and food quality control.
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