3-Chlorobenzotrifluoride (CAS 98-15-7) is a high-purity halogenated aromatic compound with the molecular formula C7H4ClF3. Key specifications include:
3-Chlorobenzotrifluoride serves as a critical intermediate in:
For optimal performance and safety:
Case Study 1: Agrochemical Production
In a recent synthesis of fluoro-containing pesticides, 3-Chlorobenzotrifluoride demonstrated exceptional reactivity as a fluorinated intermediate. Under optimized conditions (80°C, 6 hrs, K2CO3 catalyst), conversion rates exceeded 92% with minimal byproducts.
Case Study 2: Pharmaceutical Intermediate
A leading API manufacturer utilized this compound in a Buchwald-Hartwig coupling reaction, achieving 85% yield of a trifluoromethylated anti-inflammatory drug candidate. The process showed excellent reproducibility across 15 production batches.
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