Factory Supply Calcium Folinate Cas 1492-18-8 User Guide

Basic Information and Parameters
Uses of the Product
How to Use the Product
Usage Case Studies
Contact Information

Basic Information and Parameters

Calcium Folinate with CAS number 1492-18-8 is a well - known chemical compound. It is a calcium salt of folinic acid, which is a form of folate. The molecular formula of Calcium Folinate is C₂₀H₂₃CaN₇O₇, and its molecular weight is approximately 511.5 g/mol.

Factory - supplied Calcium Folinate is of high purity, ensuring the best quality for various applications. The product is usually presented as a white to yellowish - white crystalline powder. It is soluble in water, which makes it convenient for different uses. The product is stored under recommended conditions to maintain its stability and efficacy.

Uses of the Product

1. **Medical Field**: Calcium Folinate is widely used in medicine. It is an important antidote for the toxicity of folic acid antagonists such as methotrexate. In cancer chemotherapy, when high - dose methotrexate is used, Calcium Folinate is administered to rescue normal cells from the cytotoxic effects of methotrexate, reducing the side - effects on the bone marrow and gastrointestinal tract.

2. **Nutritional Supplements**: It can also be used as a nutritional supplement. Folinic acid is involved in many biochemical reactions in the body, including DNA synthesis, repair, and methylation. As a calcium salt, it is more bioavailable and can be used to supplement folate in cases where normal folate metabolism is impaired.

How to Use the Product

1. **Medical Use**: In a medical setting, the dosage of Calcium Folinate is determined by a healthcare professional based on various factors such as the patient's age, weight, medical condition, and the type of chemotherapy being used. It is usually administered either intravenously or intramuscularly. For example, in methotrexate rescue, the initial dose may be given 24 hours after the start of methotrexate infusion, and subsequent doses are adjusted according to the patient's response and methotrexate plasma levels.

2. **Nutritional Use**: When used as a nutritional supplement, the dosage is usually lower. It can be taken orally. It is recommended to follow the instructions on the product label or consult a healthcare provider for the appropriate dosage. It is important to take Calcium Folinate with food to enhance its absorption.

Usage Case Studies

Case 1: In a large - scale cancer treatment center, a patient with osteosarcoma was undergoing high - dose methotrexate chemotherapy. Without appropriate rescue, high - dose methotrexate can cause severe bone marrow suppression and gastrointestinal toxicity. Calcium Folinate was administered at a carefully calculated dosage starting 24 hours after the methotrexate infusion. The patient had significantly fewer side - effects compared to historical cases without Calcium Folinate rescue. The bone marrow function was maintained at a relatively normal level, and the patient was able to tolerate subsequent chemotherapy cycles better.

Case 2: A group of elderly patients with a history of poor folate absorption due to gastrointestinal problems were given Calcium Folinate as a nutritional supplement. After a few months of supplementation, blood tests showed an improvement in folate levels in their bodies. The patients also reported an increase in energy levels and a general improvement in well - being.

Contact Information

If you have any questions or need further information about Factory Supply Calcium Folinate Cas 1492 - 18 - 8, please feel free to contact us:

Email: info@vivalr.com

Phone: (86) 15866781826

Request A Free Quote

The Manager has Something to Say

This is William, CEO of Zhishang Chemical Co., Ltd.

Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.

About the company

Vivalr, a paragon of innovation in the chemical sector, fuses cutting - edge R & D with unwavering commitment to quality. Our product spectrum, from industrial stalwarts to fine - tuned chemicals, is a testament to our versatility.

Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
2000 square R&D center
More than 20 research and development personnel,
12 sets of research and development equipment, 10 fume hoods and 6 university laboratories have been developed in cooperation
18 patents, 140 sets of chemical synthesis processes

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
For the United States, Australia, Japan, South Korea, Sweden, France, Spain and other global more than 2000 customers to provide high-quality products and services, has won the recognition and trust of customers in the industry.

More than 12 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

Mode of Transportation

By Air, fast but expensive.

By Sea, usual and economy.

By Train, suit for middle Asia countries.

FAQ

Does it support auditing?

Environmental Protection Science and Technology Park, Zhengfeng Road, High-tech Zone, Jinan City, Shandong Province

Whether to provide samples?

Free samples can be provided, and customers only need to pay the corresponding shipping costs

Delivery time

There are stock in the warehouse, and some products need to be customized for production within 3 working days, depending on the workshop situation and production schedule

What payment methods and currencies are accepted here?

We accept payment methods such as TT, Western Union, and letter of credit, etc. Meanwhile, we support currencies like US dollars, euros, RMB, and Bitcoin, etc.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Vivalr’s delivery rate is guaranteed to be 99.99%

2000+

square meter R&D center

12+

China(set) of R&D equipment

10+

Fume hood

20+

R&D team

User’evaluation of us

"vivalr is my partner for years. Met at 2014 Shanghai CPHI Expo. Not interested then as had stable supplier. In Sep 2016, original supplier couldn't guarantee quality and delivery. Thought of Zhai and his company first. So far, have stable business relationship and good personal friendship."

Marcus Long

" In years of sourcing from China, first found working with Sincere Chemical great. They help in production, delivery and tech, saving time. When first asking Zhai for optical brightener quote, got detailed one with prices, trade details, company info, R&D and production capacity, packaging and raw material control."

Emma Kung

" Hi, I'm Kim, Zhai's partner. Don't like him much (as he never gives more for my prices, haha), but still write customer feedback. Zhai's emails help me understand product and industry. Satisfied with his work ethic. He provides quotes and helps with work details, so I can focus on other things. He's the best supplier for me."

Lisa Phoenix

" Sincere Chemical team visited our USA factory in the year of 2017. We think highly of cooperation with them. We thanked you for the past excellent orders and best product quality. We also talked about some new products for future orders. We will be still in strategic cooperation in the future and help each other."

Marcus Long

"Sincere Chemical is reliable and professional. Its team is excellent in exporting and service, giving suggestions for our new project. Satisfied with service and product quality. Vendor code: 51465768."

Emma Kung

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