Factory Supply Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester CAS 69739-34-0 User Guide

Table of Contents

• Basic Information and Parameters
• Uses of the Product
• How to Use the Product
• Usage Case Studies
• Contact Information

Basic Information and Parameters

The product is Trifluoromethanesulfonic acid tert - butyldimethylsilyl ester, with the CAS number 69739 - 34 - 0. It is factory - supplied and available at a good price. This compound is a silylating agent, which is commonly used in organic synthesis. Its chemical formula is C₉H₁₉F₃O₃SSi. The molecular weight is approximately 292.39 g/mol. It usually appears as a colorless to pale yellow liquid under normal conditions. The boiling point, melting point, and other physical properties may vary depending on the specific purity and environmental conditions. Generally, it has a relatively low melting point and a moderate boiling point, which makes it easy to handle in chemical reactions.

Uses of the Product

1. **Organic Synthesis**: It is widely used as a silylating agent. Silyl groups can protect hydroxyl groups in organic molecules during multi - step synthesis. By reacting with hydroxyl - containing compounds, it forms a silyl ether, which can prevent unwanted reactions at the hydroxyl site. After the desired reactions are completed, the silyl group can be removed under appropriate conditions, restoring the hydroxyl group.
2. **Pharmaceutical Industry**: In the synthesis of pharmaceutical intermediates, this product can play a crucial role. It can be used to introduce silicon - containing groups into drug - like molecules, which may improve the solubility, stability, and bio - availability of the final pharmaceutical products.
3. **Material Science**: It can be used in the modification of some materials. For example, it can react with the surface of inorganic materials to introduce organic functional groups, improving the compatibility between inorganic and organic phases in composite materials.

How to Use the Product

1. **Handling and Storage**: This product should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a well - sealed container to prevent exposure to air and moisture, as it may react with water and oxygen in the air. When handling, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn.
2. **Reaction Conditions**: In organic synthesis reactions, the appropriate solvent should be selected according to the nature of the reactants. Commonly used solvents include dichloromethane, tetrahydrofuran, and toluene. The reaction temperature and time also need to be carefully controlled. Generally, the reaction can be carried out at room temperature or under heating conditions, depending on the reactivity of the reactants. A catalyst may be required in some cases to accelerate the reaction rate.
3. **Purification**: After the reaction is completed, the product needs to be purified. Common purification methods include column chromatography, distillation, and recrystallization. The choice of purification method depends on the properties of the product and impurities.

Usage Case Studies

1. **Synthesis of a Pharmaceutical Intermediate**: A research group was synthesizing a new anti - cancer drug intermediate. The intermediate contained a hydroxyl group, which was prone to oxidation and other side - reactions during the synthesis process. They used Trifluoromethanesulfonic acid tert - butyldimethylsilyl ester to protect the hydroxyl group. First, they dissolved the hydroxyl - containing compound and the silylating agent in dichloromethane at room temperature. Then, a small amount of a base catalyst was added, and the reaction was stirred for 2 hours. The silyl - protected compound was obtained with a high yield. After several subsequent reactions, the silyl group was removed using a mild acid, and the target intermediate was successfully synthesized.
2. **Material Surface Modification**: In a material science project, researchers wanted to improve the compatibility between silica nanoparticles and a polymer matrix. They treated the silica nanoparticles with Trifluoromethanesulfonic acid tert - butyldimethylsilyl ester in toluene at 50°C for 4 hours. The silicon - containing groups were successfully introduced onto the surface of the silica nanoparticles. When the modified silica nanoparticles were mixed with the polymer matrix, the resulting composite material showed better mechanical properties and dispersion compared to the un - modified one.

Contact Information

If you have any questions or need more information about this product, you can contact us via email at info@vivalr.com or call us at (86) 1586678