The product we are introducing is Factory Supply Pyrrole-2-carboxaldehyde with the CAS number 1003 - 29 - 8. Pyrrole-2-carboxaldehyde is an important organic compound with its unique chemical structure and properties. The molecular formula of Pyrrole-2-carboxaldehyde is C₅H₅NO, and its molecular weight is approximately 95.1 g/mol.
It appears as a yellow to orange liquid or solid at room temperature, with a characteristic odor. In terms of solubility, it is soluble in common organic solvents such as ethanol, ether, and chloroform, but has limited solubility in water. The density of Pyrrole-2-carboxaldehyde is about 1.167 g/cm³, and its boiling point is around 213-214 °C. These physical and chemical properties play a crucial role in its various applications.
Pyrrole-2-carboxaldehyde has a wide range of applications in different fields. In the field of organic synthesis, it serves as a key intermediate. It can be used to synthesize a variety of heterocyclic compounds with potential biological activities. For example, it can participate in reactions such as condensation reactions and cycloaddition reactions to form more complex molecular structures.
In the pharmaceutical industry, Pyrrole-2-carboxaldehyde is used in the development of new drugs. Many drugs with anti - inflammatory, antibacterial, and anti - tumor activities contain pyrrole - related structures, and Pyrrole-2-carboxaldehyde can be used as a starting material to synthesize these drug candidates. In the field of materials science, it can also be used to prepare some functional materials, such as conductive polymers and fluorescent materials, due to its unique electronic structure.
When using Pyrrole-2-carboxaldehyde, safety precautions should be strictly followed. First of all, wear appropriate personal protective equipment, such as safety glasses, gloves, and a lab coat. Since it is an organic compound and may be volatile, the operation should be carried out in a well - ventilated fume hood to avoid inhalation of its vapors.
In the process of chemical reactions, accurately measure the required amount of Pyrrole-2-carboxaldehyde according to the reaction formula. It can be added dropwise or in batches during the reaction, depending on the specific reaction conditions. After use, it should be properly stored in a cool, dry place away from light and heat sources. Keep it tightly sealed to prevent oxidation and contamination.
Case 1: Drug Synthesis
A pharmaceutical research team was working on the development of a new anti - inflammatory drug. They used Pyrrole-2-carboxaldehyde as a key intermediate. By reacting it with a specific amine compound under certain reaction conditions, they successfully synthesized a new heterocyclic compound. After a series of optimization and modification steps, the final drug candidate showed significant anti - inflammatory activity in in - vitro and in - vivo experiments. This case shows that Pyrrole-2-carboxaldehyde can play a crucial role in the discovery and development of new drugs.
Case 2: Material Preparation
A materials science research group was interested in preparing a new type of fluorescent material. They used Pyrrole-2-carboxaldehyde as a building block. Through a polymerization reaction with other monomers, they obtained a polymer material with excellent fluorescent properties. This material can be used in bio - imaging and sensor applications. The unique chemical structure of Pyrrole-2-carboxaldehyde contributed to the good fluorescence performance of the final material.
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