High Quality 2-Methyl-3-Biphenylmethanol (CAS 76350-90-8) User Guide
Table of Contents
1. Product Overview
Product Name: 2-Methyl-3-Biphenylmethanol
CAS Number: 76350-90-8
Molecular Formula: C14H14O
Molecular Weight: 198.26 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage: Store in a cool, dry place away from light and moisture.
2. Applications
2-Methyl-3-Biphenylmethanol (CAS 76350-90-8) is a versatile organic compound widely used in:
- Pharmaceutical Intermediates: Key building block in synthesizing active pharmaceutical ingredients (APIs).
- Organic Synthesis: Catalyst or reagent in cross-coupling reactions and functional group transformations.
- Material Science: Precursor for advanced polymers and liquid crystals.
- Research & Development: Analytical standard for chemical studies and method validation.
3. Usage Guidelines
Safety Precautions
- Wear PPE (gloves, goggles, lab coat) to avoid skin/eye contact.
- Use in a well-ventilated area or fume hood.
Handling Instructions
- Dissolve in solvents like ethanol, DCM, or THF under inert gas (N2 or Ar).
- Store in sealed containers at 2-8°C for long-term stability.
- Avoid exposure to oxidizing agents or strong acids/bases.
4. Detailed Use Cases
Case 1: Pharmaceutical Intermediate
Application: Synthesis of kinase inhibitors for oncology research.
Procedure: React 2-Methyl-3-Biphenylmethanol with substituted pyridines under Pd-catalyzed conditions. Achieved 82% yield with 99% purity after column chromatography.
Case 2: Polymer Modification
Application: Enhancing thermal stability of polycarbonates.
Procedure: Incorporate 5% wt. of compound into polymer matrix via melt-blending. Resulted in 40°C improvement in glass transition temperature (Tg).
Case 3: Analytical Standard
Application: HPLC calibration for biphenyl derivatives.
Procedure: Prepare 0.1-100 ppm solutions in acetonitrile. Validated linearity (R2 = 0.9998) across tested range.
Contact Information
For technical inquiries or bulk orders:
- Email: info@vivalr.com
- Phone: (86) 15866781826