High Quality Tris(hydroxymethyl)nitromethane (CAS 126-11-4) User Guide
Table of Contents
1. Product Overview
Tris(hydroxymethyl)nitromethane (CAS 126-11-4) is a high-purity chemical compound with the molecular formula C4H9NO5. Key specifications include:
- Molecular Weight: 151.12 g/mol
- Appearance: White crystalline powder
- Purity: ≥98%
- Storage: Keep in a cool, dry place at 2-8°C
- Solubility: Soluble in water and polar organic solvents
2. Applications
Tris(hydroxymethyl)nitromethane is widely used in:
- Organic Synthesis: As a versatile intermediate for pharmaceuticals and agrochemicals.
- Biochemical Research: In buffer preparation and enzyme stabilization.
- Material Science: As a crosslinking agent for polymers and resins.
- Analytical Chemistry: For derivatization in chromatography and spectrometry.
3. Usage Instructions
Safety Precautions
- Wear PPE (gloves, goggles, lab coat).
- Work in a well-ventilated area or fume hood.
Preparation Steps
- Weigh the required quantity using a calibrated balance.
- Dissolve in distilled water or a compatible solvent (0.1-1M concentration recommended).
- Stir at room temperature until fully dissolved (heating up to 40°C may accelerate dissolution).
4. Usage Examples
Example 1: Pharmaceutical Intermediate Synthesis
Scenario: Synthesis of antiviral drug precursors.
Process: 10g of Tris(hydroxymethyl)nitromethane was reacted with ethyl bromoacetate in DMF at 60°C for 6 hours, yielding 85% of the target intermediate.
Example 2: Polymer Stabilization
Scenario: Enhancing thermal stability of epoxy resins.
Process: Adding 2% (w/w) of the compound to epoxy formulations increased decomposition temperature by 22°C in TGA analysis.
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