2-Keto-L-Gulonic Acid (CAS 342385-52-8) - High-Quality Factory Supply

Product Name: 2-Keto-L-Gulonic Acid

CAS Number: 342385-52-8

Molecular Formula: C6H10O7

Appearance: White to off-white crystalline powder

Purity: ≥98% (HPLC)

Storage: Store in a cool, dry place away from light and moisture.

Key Applications of 2-Keto-L-Gulonic Acid

2-Keto-L-Gulonic Acid is a critical intermediate in the production of Vitamin C (Ascorbic Acid). Its primary uses include:

• Pharmaceutical industry: Precursor for synthesizing Vitamin C and derivatives.
• Food additives: Used in antioxidant formulations and nutritional supplements.
• Biochemical research: Substrate in enzymatic studies and metabolic pathway analysis.
• Industrial applications: Raw material for specialty chemicals and cosmetics.

Guidelines for Safe and Effective Use

Step 1: Wear appropriate PPE (gloves, goggles, lab coat) during handling.

Step 2: Dissolve in purified water or ethanol at a concentration of 5-10% w/v.

Step 3: Maintain pH between 6.0-7.0 for optimal stability during reactions.

Step 4: Store unused material in airtight containers at 2-8°C.

Detailed Use Case: Vitamin C Synthesis

Scenario: Large-scale production of Vitamin C in a pharmaceutical facility.

Process:

1. Mix 2-Keto-L-Gulonic Acid with sodium hydroxide (1:1.2 molar ratio).
2. Heat to 60°C under nitrogen atmosphere for 3 hours.
3. Neutralize with HCl to pH 5.5-6.0 to precipitate Ascorbic Acid.
4. Filter and purify via recrystallization (yield: 85-92%).

Result: Achieved 99.2% purity Vitamin C, meeting USP standards.

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