(S)-5-Hydroxymethyldihydrofuran-2-one (CAS 32780-06-6) is a high-purity chiral intermediate with the molecular formula C6H8O3 and a molecular weight of 128.13 g/mol. This compound appears as a white to off-white crystalline powder and boasts a purity of ≥98% (HPLC). It is stable under recommended storage conditions: kept in a tightly sealed container at 2-8°C, protected from light and moisture.
This compound is widely used in:
In the synthesis of Oseltamivir Phosphate (Tamiflu®), researchers utilized (S)-5-Hydroxymethyldihydrofuran-2-one as a stereospecific intermediate. The compound's enantiomeric purity (>99% ee) ensured high yield (82%) in the final coupling reaction.
A leading skincare brand incorporated 0.5-1.5% of this compound in their anti-aging serum, leveraging its humectant properties to improve skin hydration by 27% in clinical trials.
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