
Our product, High Quality itraconazole cas 84625-61-6 With Best Price, is a well - recognized pharmaceutical compound. Itraconazole is a synthetic triazole antifungal agent. The CAS number 84625 - 61 - 6 uniquely identifies this chemical substance.
It is available in various forms such as capsules, oral solution, and intravenous formulation. The molecular formula of itraconazole is C₃₅H₃₈Cl₂N₄O₇, and its molecular weight is approximately 705.60 g/mol. It is a white to slightly yellowish powder with a melting point around 166 - 168°C. Solubility of itraconazole is poor in water but soluble in organic solvents like methanol and chloroform.
Itraconazole is primarily used for the treatment of a wide range of fungal infections. It has broad - spectrum antifungal activity against many types of fungi including dermatophytes, yeasts, and dimorphic fungi.
In the field of dermatology, it is used to treat nail fungal infections (onychomycosis), tinea corporis (ringworm of the body), tinea cruris (jock itch), and tinea pedis (athlete's foot). In the internal medicine, it can be used to treat systemic fungal infections such as aspergillosis, candidiasis, and histoplasmosis in immunocompromised patients. It works by inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane, thereby disrupting the integrity and function of the fungal cell.
The usage of itraconazole depends on the form of the product and the type of infection being treated. For oral capsules, it is usually taken with a full meal to enhance absorption. The dosage is determined by the severity of the infection and the patient's condition. For example, in the treatment of onychomycosis, a typical dosage may be 200 mg once or twice daily for several months.
The oral solution is often used for the treatment of oral and esophageal candidiasis. It should be swished around in the mouth thoroughly before swallowing. The intravenous formulation is used in more severe systemic fungal infections and is administered under the supervision of medical professionals in a hospital setting. It is crucial to follow the doctor's instructions precisely when using itraconazole, and the treatment duration should not be shortened or extended without medical advice.
Case 1: A 45 - year - old male patient presented with toenail onychomycosis that had persisted for over a year. He was prescribed itraconazole capsules 200 mg twice daily for three consecutive months. After the treatment, fungal cultures from the affected nails became negative, and there was significant improvement in the appearance of the nails. The patient also reported no major side - effects during the treatment period.
Case 2: A 60 - year - old immunocompromised female patient was diagnosed with invasive aspergillosis. She was initially treated with intravenous itraconazole in the hospital. After a week of treatment, her symptoms such as cough and shortness of breath started to improve. The treatment was then continued with oral itraconazole capsules for another six weeks. Follow - up imaging showed significant reduction in the fungal lesions, and the patient's overall condition improved.
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