Warfarin Sodium with the CAS number 51821 - 81 - 9 is a high - quality product that offers a favorable price. It is a well - known anticoagulant medication. The chemical formula of Warfarin Sodium is C₁₉H₁₆NaO₄, and it has a molecular weight of approximately 330.32 g/mol. Physically, it usually appears as a white to off - white powder. This product is highly soluble in water, making it suitable for various pharmaceutical formulations. It has a melting point in the range of around 160 - 162°C. The high - quality standard ensures that it meets strict purity requirements, typically with a purity level of over 98%.
Warfarin Sodium is primarily used as an anticoagulant in the medical field. It works by inhibiting the synthesis of vitamin K - dependent clotting factors in the liver. This makes it extremely useful in preventing and treating blood clots. In patients who have had atrial fibrillation, it helps reduce the risk of stroke by preventing the formation of blood clots in the heart that could travel to the brain. It is also commonly prescribed after surgeries, such as hip or knee replacement, to prevent deep vein thrombosis (DVT). Additionally, it is used in the treatment of pulmonary embolism, where a blood clot has traveled to the lungs, potentially blocking blood flow.
The usage of Warfarin Sodium should be strictly guided by a healthcare professional. The dosage is highly individualized and depends on factors such as the patient's age, weight, medical condition, and the presence of other medications. Usually, it is taken orally in tablet form. The initial dose is often relatively low, and then it is gradually adjusted based on the patient's international normalized ratio (INR), which measures the blood's clotting ability. Patients are required to have regular blood tests to monitor their INR levels, typically once or twice a week initially and then less frequently as the dosage stabilizes. It is important to take the medication at the same time every day to maintain a consistent level in the blood. Patients should also be aware that certain foods high in vitamin K, such as leafy green vegetables, can interact with Warfarin Sodium and affect its effectiveness. Therefore, it is necessary to maintain a relatively stable diet in terms of vitamin K intake.
Case 1: A 65 - year - old male patient was diagnosed with atrial fibrillation. He was started on Warfarin Sodium at an initial dose of 2.5 mg per day. Regular INR monitoring was carried out, and the dosage was adjusted gradually over a period of several weeks. After three months, his INR was stable within the therapeutic range of 2 - 3. He had no episodes of stroke or other blood - clot - related complications during the follow - up period of one year. His quality of life improved, and he was able to resume his normal daily activities.
Case 2: A 50 - year - old female who had undergone a total knee replacement surgery was prescribed Warfarin Sodium to prevent DVT. She started with a dose of 3 mg per day. Her INR was monitored closely, and within two weeks, the dosage was adjusted to 4 mg per day to keep her INR in the appropriate range. She completed a six - week course of treatment without developing any signs of DVT. Follow - up ultrasound examinations confirmed the absence of blood clots in her legs.
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