Factory Supply 5-Chlorothiophene-2-carbonyl chloride CAS 42518-98-9 With Best Price
Table of Contents
1. Product Overview
Product Name: 5-Chlorothiophene-2-carbonyl chloride
CAS Number: 42518-98-9
Molecular Formula: C5H2Cl2OS
Molecular Weight: 193.09 g/mol
Appearance: Clear to pale yellow liquid
Purity: ≥98% (HPLC)
Storage: Store at 2-8°C in a dry, airtight container
2. Key Applications
5-Chlorothiophene-2-carbonyl chloride (CAS 42518-98-9) is a high-value chemical intermediate widely used in:
- Pharmaceuticals: Synthesis of active pharmaceutical ingredients (APIs) for antibiotics and antivirals.
- Agrochemicals: Production of herbicides and fungicides.
- Material Science: Building block for advanced polymers and electronic materials.
3. Usage Guidelines
- Handle in a well-ventilated area with PPE (gloves, goggles, lab coat).
- Use anhydrous conditions for reactions to avoid hydrolysis.
- Dilute with inert solvents (e.g., THF, DCM) before use in coupling reactions.
- Store away from moisture and oxidizing agents.
4. Application Case Studies
Case 1: Synthesis of Antibacterial Agents
5-Chlorothiophene-2-carbonyl chloride is reacted with aminopyridine derivatives to form acylated intermediates, critical for developing novel quinolone antibiotics.
Case 2: Herbicide Production
Used as a key intermediate in synthesizing thiophene-based herbicides, enabling selective weed control in crops like corn and soybeans.
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