High Quality Sevelamer Carbonate, with the CAS number 845273 - 93 - 0, is a high - quality product available at the best price. Chemically, it is a polymer - based phosphate binder. The high - quality standard of this product ensures its stability and purity, which are crucial for its various applications.
Sevelamer carbonate is a cross - linked polymer formed by the copolymerization of allylamine and epichlorohydrin, followed by carbonation. Its molecular structure gives it unique physical and chemical properties. It is a white to off - white powder, and it has good solubility characteristics in certain solvents, which makes it suitable for different pharmaceutical formulations.
The primary use of High Quality Sevelamer Carbonate is in the medical field, especially for patients with chronic kidney disease (CKD). In patients with CKD, the kidneys' ability to excrete phosphate is impaired, leading to hyperphosphatemia (high levels of phosphate in the blood). This can cause various complications such as bone disease, vascular calcification, and increased cardiovascular risk.
Sevelamer carbonate acts as a phosphate binder. When taken orally, it binds to dietary phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream. By reducing the amount of phosphate absorbed, it helps to control serum phosphate levels in CKD patients, thereby reducing the risk of associated complications. Additionally, it may also have beneficial effects on lipid metabolism, as some studies have shown that it can lower LDL cholesterol levels.
High Quality Sevelamer Carbonate is usually administered orally. The dosage should be determined by a healthcare professional based on the patient's serum phosphate levels, diet, and other individual factors. It is typically taken with meals to maximize its binding effect on dietary phosphate.
Patients should swallow the tablets whole and should not chew, crush, or split them, as this may affect the release and efficacy of the product. If a patient misses a dose, they should take it as soon as they remember, unless it is close to the time for the next dose. In that case, they should skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for a missed one.
Case 1: Mr. Smith, a 60 - year - old man with stage 4 chronic kidney disease, was suffering from hyperphosphatemia. His serum phosphate levels were consistently above the normal range, and he was at risk of developing bone pain and vascular calcification. After starting treatment with High Quality Sevelamer Carbonate at a dosage of 800 mg three times a day with meals, his serum phosphate levels gradually decreased. After 3 months of treatment, his phosphate levels were within the normal range, and he reported a significant improvement in his overall well - being. He also noticed a decrease in his LDL cholesterol levels.
Case 2: Mrs. Johnson, a 55 - year - old woman on hemodialysis, had persistent hyperphosphatemia despite dietary restrictions. She was started on Sevelamer carbonate with an initial dosage of 400 mg three times a day. Over the next few months, the dosage was adjusted based on her phosphate levels. Eventually, her serum phosphate levels were well - controlled, and the progression of her bone disease was halted. The regular use of High Quality Sevelamer Carbonate helped her maintain a better quality of life during her hemodialysis treatment.
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