Factory Supply Baricitinib CAS 1187594-09-7 With Best Price
Table of Contents
1. Product Information
Product Name: Baricitinib
CAS Number: 1187594-09-7
Molecular Formula: C16H17N7O2S
Appearance: White to off-white powder
Purity: ≥98% (HPLC)
Storage Conditions: Store at 2-8°C in a dry, dark place.
2. Uses of Baricitinib
Baricitinib is a Janus kinase (JAK) inhibitor primarily used for:
- Treatment of moderate-to-severe rheumatoid arthritis in adults.
- Management of COVID-19 in hospitalized patients requiring supplemental oxygen.
- Potential applications in autoimmune disorders like alopecia areata and psoriasis (under clinical research).
3. How to Use Baricitinib
Dosage Guidelines:
- Rheumatoid Arthritis: 2 mg once daily, orally, with or without food.
- COVID-19: 4 mg once daily for up to 14 days, combined with antiviral therapies.
Precautions:
- Monitor for infections, liver function, and blood counts during treatment.
- Contraindicated in patients with active tuberculosis or severe hepatic impairment.
4. Application Cases
Case 1: Rheumatoid Arthritis Management
A 52-year-old patient with refractory rheumatoid arthritis showed significant reduction in joint swelling and pain after 12 weeks of Baricitinib (2 mg/day), with no adverse events reported.
Case 2: COVID-19 Treatment
In a clinical trial, Baricitinib (4 mg/day) combined with remdesivir reduced recovery time by 1 day in hospitalized COVID-19 patients, per NIH guidelines.