Product Name: 1-Octadecanoyl-2-[cis-9-octadecenoyl]-sn-glycero-3-phosphocholine (SOPC)
CAS Number: 56421-10-4
Molecular Formula: C44H85NO8P
Molecular Weight: 802.12 g/mol
Appearance: White to off-white powder
Purity: ≥98% (HPLC)
Storage: Store at -20°C in airtight containers, protected from light and moisture.
SOPC is a synthetic phospholipid widely used in:
Step 1: Allow the product to reach room temperature before opening to prevent moisture absorption.
Step 2: Weigh the required quantity using a calibrated balance in a controlled environment.
Step 3: Dissolve SOPC in chloroform or ethanol (1-10 mg/mL) for lipid film preparation.
Step 4: Hydrate the lipid film with aqueous buffers (e.g., PBS) under vortexing or sonication to form liposomes.
Safety: Use PPE (gloves, goggles) and work in a well-ventilated area.
SOPC is mixed with cholesterol (55:45 molar ratio) to create stable liposomes for encapsulating anticancer drugs like doxorubicin. The formulation demonstrated >85% encapsulation efficiency and sustained release over 72 hours.
Researchers used SOPC bilayers to study temperature-dependent membrane fluidity via fluorescence anisotropy. Results showed phase transition at 32°C, critical for understanding membrane-protein interactions.
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