Carbobenzoxyhydrazide CAS 5331-43-1 User Guide: Applications, Usage, and Case Studies

1. Product Overview
2. Key Applications
3. Usage Instructions
4. Case Studies
5. Contact Information

1. Product Overview

Carbobenzoxyhydrazide (CAS 5331-43-1) is a specialized chemical compound widely used in organic synthesis and pharmaceutical research. Below are its key specifications:

Chemical Name: Carbobenzoxyhydrazide
CAS Number: 5331-43-1
Molecular Formula: C₈H₁₀N₂O₂
Molecular Weight: 166.18 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage: Store in a cool, dry place at 2-8°C

2. Key Applications

Carbobenzoxyhydrazide is primarily utilized in:

Peptide Synthesis: Acts as a protecting group for amines during solid-phase peptide synthesis.
Pharmaceutical Intermediates: Used in the production of antibiotics, antivirals, and anticancer agents.
Organic Synthesis: Facilitates the formation of hydrazides and hydrazones in complex reactions.
Research & Development: Critical in academic and industrial labs for experimental studies.

3. Usage Instructions

Follow these steps for safe and effective use:

Safety Precautions: Wear PPE (gloves, goggles, lab coat) and work in a well-ventilated area.
Dissolution: Dissolve in polar solvents like DMF, DMSO, or ethanol at room temperature.
Reaction Conditions: Use under inert atmosphere (N₂ or Ar) for sensitive reactions.
Deprotection: Remove the Cbz group via hydrogenolysis or acidic hydrolysis as required.
Storage: Keep the container tightly sealed to avoid moisture absorption.

4. Case Studies

Case Study 1: Synthesis of Cbz-Protected Amine Intermediate

Objective: Prepare a Cbz-protected amine for antibiotic research.

Step 1: Dissolve 5g Carbobenzoxyhydrazide in 50ml DMF.
Step 2: Add 10mmol primary amine and stir at 25°C for 4 hours.
Step 3: Isolate the product via filtration (yield: 92%).
Result: High-purity Cbz-amine intermediate suitable for further functionalization.

Case Study 2: Hydrazone Formation for Anticancer Drug Development

Objective: Create a hydrazone linker for targeted drug delivery.

Step 1: React Carbobenzoxyhydrazide with aldehyde derivatives in ethanol.
Step 2: Monitor reaction progress via TLC (completion in 2 hours).
Step 3: Purify the hydrazone product using column chromatography.
Result: Stable hydrazone linker with 85% efficiency in drug conjugation.

5. Contact Information

For inquiries or orders, contact our team:

Email: info@vivalr.com
Phone: (86) 15866781826

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About the company

Vivalr, a paragon of innovation in the chemical sector, fuses cutting - edge R & D with unwavering commitment to quality. Our product spectrum, from industrial stalwarts to fine - tuned chemicals, is a testament to our versatility.

Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
2000 square R&D center
More than 20 research and development personnel,
12 sets of research and development equipment, 10 fume hoods and 6 university laboratories have been developed in cooperation
18 patents, 140 sets of chemical synthesis processes

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
For the United States, Australia, Japan, South Korea, Sweden, France, Spain and other global more than 2000 customers to provide high-quality products and services, has won the recognition and trust of customers in the industry.

More than 12 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

Mode of Transportation

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By Sea, usual and economy.

By Train, suit for middle Asia countries.

FAQ

Does it support auditing?

Environmental Protection Science and Technology Park, Zhengfeng Road, High-tech Zone, Jinan City, Shandong Province

Whether to provide samples?

Free samples can be provided, and customers only need to pay the corresponding shipping costs

Delivery time

There are stock in the warehouse, and some products need to be customized for production within 3 working days, depending on the workshop situation and production schedule

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Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Vivalr’s delivery rate is guaranteed to be 99.99%

2000+

square meter R&D center

12+

China(set) of R&D equipment

10+

Fume hood

20+

R&D team

User’evaluation of us

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