Calcium phosphate tribasic, with the CAS number 12167 - 74 - 7, is a high - quality chemical product offered at a low price. Chemically, its formula is Ca₃(PO₄)₂. It is a white, odorless powder that is insoluble in water but soluble in dilute acids.
The product typically has a high purity level. The calcium content is around 38 - 40%, and the phosphate content is approximately 58 - 60%. It has a density of about 3.14 g/cm³. The particle size can be adjusted according to different requirements, usually ranging from a few microns to tens of microns.
In the food industry, calcium phosphate tribasic serves as an anti - caking agent. It helps to prevent powdered foods such as spices, milk powder, and baking powder from clumping together, ensuring a free - flowing and consistent product. It can also be used as a calcium supplement in fortified foods, enhancing the nutritional value.
In the pharmaceutical field, it is a common excipient. It can be used in tablet and capsule formulations as a filler and diluent. Its biocompatibility and slow dissolution rate make it suitable for controlled - release drug delivery systems, allowing for a gradual release of the active pharmaceutical ingredient.
In the dental industry, calcium phosphate tribasic is used in the production of dental cements and fillings. Its chemical properties are similar to those of tooth enamel, making it an ideal material for restoring and repairing teeth.
When using calcium phosphate tribasic in the food industry, it should be added during the mixing process. The recommended dosage usually depends on the type of food product, but generally, it is in the range of 0.1 - 1% by weight. For example, when making spice blends, add an appropriate amount of the product and mix thoroughly to ensure even distribution.
In pharmaceutical manufacturing, it needs to be carefully blended with other excipients and the active ingredient. The mixing process should be carried out under controlled conditions to ensure the uniformity of the final product. The amount used is determined by the formulation requirements of the specific drug.
In the dental industry, it is mixed with other dental materials according to specific formulas. The mixing ratio and the way of mixing (such as manual or mechanical mixing) are crucial for achieving the desired properties of the dental cement or filling material.
**Food Industry Case Study**: A spice manufacturer was facing the problem of clumping in their product, which led to an inconsistent customer experience. After adding calcium phosphate tribasic at a dosage of 0.3% by weight during the mixing process, the spices remained free - flowing for an extended period. The product's shelf - life was also improved, and customer complaints about clumping significantly decreased.
**Pharmaceutical Case Study**: A pharmaceutical company was developing a controlled - release tablet for a pain - relief drug. By using calcium phosphate tribasic as a filler and part of the controlled - release matrix, they were able to achieve a steady release of the drug over a 12 - hour period. Clinical trials showed that the new formulation provided more consistent pain relief compared to the previous immediate - release version.
**Dental Case Study**: A dental clinic was using a new dental cement formulation that included calcium phosphate tribasic. The cement had better adhesion to the tooth surface and provided a more natural - looking restoration. Patients reported less discomfort after the dental procedure, and the durability of the fillings was significantly improved.
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