Tropolone, with the CAS number 533-75-5, is an important organic compound. Its chemical formula is C₇H₆O₂. The molecular weight of tropolone is approximately 122.12 g/mol. It exists as a white to off - white crystalline solid at room temperature. Tropolone has a melting point in the range of 50 - 52 °C and a boiling point around 110 - 112 °C at 12 mmHg. It is sparingly soluble in water but soluble in common organic solvents such as ethanol, acetone, and chloroform. The compound is known for its unique seven - membered ring structure with an enolic hydroxyl group, which imparts certain chemical reactivities and biological activities.
Tropolone has a wide range of applications in various fields. In the field of medicine, it has shown potential antibacterial and antifungal properties. It can be used in the development of new drugs to treat skin infections caused by bacteria and fungi. For example, it may be incorporated into topical creams or ointments to combat common skin pathogens. In the agricultural industry, tropolone can act as a plant growth regulator. It can promote the growth of certain crops by regulating physiological processes such as cell division and elongation. Additionally, it can enhance the resistance of plants to environmental stresses such as drought and disease. In the chemical industry, tropolone serves as a valuable intermediate for the synthesis of other complex organic compounds. It can be used in the preparation of dyes, fragrances, and polymers.
When using tropolone in the medical field, it is usually formulated into appropriate pharmaceutical preparations. For topical applications, it is mixed with suitable carriers such as petrolatum or lanolin to form creams or ointments. The concentration of tropolone in these preparations should be carefully determined based on the specific application and the nature of the infection. In the agricultural sector, tropolone can be applied as a foliar spray or soil drench. When using it as a foliar spray, it should be diluted with water to an appropriate concentration according to the crop type and growth stage. The spray should be evenly distributed on the leaves to ensure effective absorption. When used as a soil drench, it is mixed with water and poured around the base of the plants. In the chemical synthesis, tropolone is used in organic reactions under controlled conditions. It is usually dissolved in an appropriate organic solvent and reacted with other reagents according to the reaction mechanism and requirements.
Medical Case: A dermatology clinic conducted a trial on the use of a tropolone - containing cream to treat patients with dermatophyte infections. A total of 50 patients were involved in the study. They were divided into two groups: a treatment group using the tropolone cream and a control group using a placebo cream. After a 4 - week treatment period, 80% of the patients in the treatment group showed significant improvement in symptoms such as itching, redness, and scaling, while only 20% of the control group showed some improvement. This indicates that tropolone has a good therapeutic effect on dermatophyte infections.
Agricultural Case: A farm tested the effect of tropolone on tomato plants. They applied tropolone as a foliar spray at different growth stages of the tomatoes. The results showed that the treated tomato plants had a higher fruit set rate and larger fruit size compared to the untreated plants. The yield of the treated plants increased by about 30% compared to the control group, and the tomatoes were more resistant to diseases such as early blight.
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