Our product, High Quality Rapamycin Cas 53123 - 88 - 9 With Best Price, is a high - purity chemical compound. Rapamycin, also known as sirolimus, has the chemical formula C₅₁H₇₉NO₁₃. It has a molecular weight of approximately 914.17 g/mol. This product is presented in a white to off - white powder form. It has a melting point range of around 183 - 185 °C. The solubility of rapamycin in common solvents varies; it is soluble in organic solvents such as methanol, ethanol, and chloroform, but poorly soluble in water. High - quality control measures are implemented during its production process, ensuring a purity level of over 98%, which meets the strict requirements of various research and industrial applications.
Rapamycin has a wide range of applications in different fields. In the medical field, it is mainly used as an immunosuppressant. After organ transplantation, it can prevent the immune system from rejecting the transplanted organ by inhibiting the activation and proliferation of T - lymphocytes. It is also being investigated for its potential anti - cancer properties. Rapamycin can block the mTOR (mammalian target of rapamycin) pathway, which plays a key role in cell growth, proliferation, and survival. By inhibiting mTOR, rapamycin may slow down the growth and spread of cancer cells.
In the field of aging research, rapamycin has shown promise in extending lifespan and improving healthspan in various model organisms. It can regulate cellular metabolism, autophagy, and stress response, which are all related to the aging process.
In the biotechnology and pharmaceutical industries, rapamycin serves as an important research tool. Scientists use it to study signal transduction pathways, cell cycle regulation, and other fundamental biological processes.
When using High Quality Rapamycin Cas 53123 - 88 - 9, it is crucial to follow proper safety protocols. First, make sure to wear appropriate personal protective equipment, including gloves, safety glasses, and a lab coat.
For research purposes, rapamycin is usually prepared as a stock solution. Dissolve the powder in an appropriate organic solvent, such as methanol or ethanol, to obtain a high - concentration stock solution. The stock solution can then be diluted to the desired working concentration using cell culture media or other appropriate buffers.
The dosage of rapamycin depends on the specific application. In cell culture experiments, the working concentration typically ranges from a few nanomolar to micromolar. In in - vivo experiments, the dosage needs to be carefully determined based on the animal model, route of administration, and research purpose. Administration routes can include oral gavage, intraperitoneal injection, or intravenous injection.
Case 1: Organ Transplantation
A patient underwent a kidney transplantation. To prevent organ rejection, a regimen of rapamycin was started immediately after the surgery. The patient was administered rapamycin orally at a daily dose of 2 mg. Regular blood tests were conducted to monitor the drug concentration in the blood and the patient's immune status. Over a period of one year, the patient showed no signs of organ rejection. The levels of immune - related markers in the blood remained within the normal range, indicating that the rapamycin was effectively suppressing the immune response.
Case 2: Cancer Research
In a pre - clinical study, a group of mice with breast cancer were treated with rapamycin. The rapamycin was administered intraperitoneally at a dose of 1 mg/kg twice a week. After eight weeks of treatment, the tumors in the treated mice showed a significant reduction in size compared to the control group. Immunohistochemical analysis revealed that the mTOR pathway in the tumor cells was effectively inhibited, leading to decreased cell proliferation and increased apoptosis.
If you have any questions or need further information about our product, High Quality Rapamycin Cas 53123 - 88 - 9, please feel free to contact us. Our email address is info@vivalr.com, and our phone number is (86) 15866781826.
This is William, CEO of Zhishang Chemical Co., Ltd.
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