4-iodoimidazole with the CAS number 71759 - 89 - 2 is a high - quality chemical product. This product is known for its purity and is offered at the best price in the market. The molecular formula of 4 - iodoimidazole is C₃H₃IN₂. It has a molecular weight of approximately 210. The appearance of 4 - iodoimidazole is typically a white to off - white crystalline powder. It is soluble in some organic solvents such as dimethyl sulfoxide (DMSO) and ethanol, which makes it suitable for a variety of chemical reactions.
4 - iodoimidazole has multiple important uses in the field of chemistry. In organic synthesis, it serves as a key intermediate. It can participate in various substitution reactions, coupling reactions, and cyclization reactions. For example, it can be used in the synthesis of heterocyclic compounds, which are widely used in the pharmaceutical industry. Many drugs contain heterocyclic structures, and 4 - iodoimidazole can be a crucial building block for constructing these structures. Additionally, it can be used in the development of new materials. Some functional materials may require specific chemical groups provided by 4 - iodoimidazole to achieve desired properties such as conductivity or optical activity.
When using 4 - iodoimidazole, proper safety precautions should be taken. It is recommended to wear appropriate personal protective equipment, including gloves and goggles. The product should be stored in a cool, dry place away from direct sunlight and sources of heat. Before use, carefully read the material safety data sheet (MSDS) for detailed information on handling and storage. When conducting reactions, accurate measurement of the amount of 4 - iodoimidazole is essential. Usually, it is added to the reaction system in a specific molar ratio according to the reaction requirements. After the reaction, standard purification techniques such as recrystallization or chromatography can be used to obtain the desired product.
Case 1: Synthesis of a Pharmaceutical Intermediate
In a pharmaceutical research project, scientists aimed to synthesize a new anti - cancer drug intermediate. 4 - iodoimidazole was used as a starting material. First, it was reacted with a specific aryl halide in the presence of a palladium catalyst through a Suzuki - Miyaura coupling reaction. The reaction was carried out in a solvent mixture of toluene and water at a specific temperature and pH. After purification by column chromatography, a high - purity intermediate was obtained. This intermediate was then further modified through a series of reactions to form the final anti - cancer drug candidate.
Case 2: Development of a Functional Polymer
A research group was working on developing a new type of conductive polymer. 4 - iodoimidazole was incorporated into the polymer backbone through a polymerization reaction. The resulting polymer showed improved conductivity and stability. The reaction conditions were carefully optimized, including the reaction temperature, time, and the ratio of monomers. The polymer was characterized by various techniques such as nuclear magnetic resonance (NMR) and infrared spectroscopy (IR) to confirm its structure and properties.
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