Factory Supply Hydroxypropyl-beta-cyclodextrin HPBCD CAS 94035-02-6/128446-35-5 User Guide

Basic Information and Parameters
Uses of the Product
How to Use the Product
Usage Case Studies
Contact Information

Basic Information and Parameters

Hydroxypropyl-beta-cyclodextrin (HPBCD) is a chemically modified cyclic oligosaccharide. The product with CAS numbers 94035-02-6/128446-35-5 is a popular choice in various industries due to its unique properties.

Chemical Structure: HPBCD is derived from beta - cyclodextrin by substituting some of the hydroxyl groups with hydroxypropyl groups. This modification enhances its solubility and other functional properties compared to the unmodified beta - cyclodextrin.

Appearance: It typically appears as a white, odorless, and free - flowing powder.

Solubility: One of the significant advantages of HPBCD is its high solubility in water. It can dissolve readily, even at relatively high concentrations, which makes it suitable for a wide range of applications.

Purity: Our factory - supplied HPBCD has a high purity level, ensuring consistent performance in different applications.

Uses of the Product

Pharmaceutical Industry: HPBCD is widely used as a solubilizing agent in pharmaceuticals. It can form inclusion complexes with poorly soluble drugs, improving their solubility, bioavailability, and stability. This is particularly important for oral, parenteral, and topical drug formulations.

Food Industry: In the food industry, HPBCD can be used as a flavor encapsulant. It can trap volatile flavor compounds, protecting them from oxidation, evaporation, and degradation. It also helps to improve the dispersion and stability of flavors in food products.

Cosmetic Industry: HPBCD can be incorporated into cosmetic formulations to enhance the solubility and stability of active ingredients. It can also improve the skin - feel of products and increase the effectiveness of certain cosmetic agents.

Analytical Chemistry: It is used in analytical chemistry as a chiral selector in chromatography. HPBCD can separate enantiomers due to its unique molecular structure and chiral properties.

How to Use the Product

Solubilization in Pharmaceuticals: When using HPBCD to solubilize drugs, first, weigh the appropriate amount of HPBCD according to the solubility requirements of the drug. Then, add it to an aqueous solution under gentle stirring. Next, gradually add the drug to the solution and continue stirring until the drug is completely dissolved. The optimal ratio of HPBCD to the drug needs to be determined through pre - formulation studies.

Flavor Encapsulation in Food: For flavor encapsulation, dissolve HPBCD in water at an appropriate concentration. Add the flavor compound to the HPBCD solution under high - speed stirring. The flavor will be encapsulated within the HPBCD cavity. The encapsulated flavor can then be added to the food product during the manufacturing process.

Use in Cosmetics: In cosmetic formulations, HPBCD can be added to the water phase of the product. Heat the water phase to an appropriate temperature (usually around 60 - 70°C) and add HPBCD with stirring until it is completely dissolved. Then, add other ingredients as per the formulation requirements.

Usage Case Studies

Pharmaceutical Case: A pharmaceutical company was developing an oral drug with poor solubility. By using HPBCD as a solubilizing agent, they were able to increase the solubility of the drug by more than 10 - fold. This led to improved bioavailability in pre - clinical studies. Patients who took the new formulation showed better therapeutic responses compared to the original poorly soluble formulation.

Food Case: A food manufacturer wanted to enhance the stability of a fruit - flavored beverage. They used HPBCD to encapsulate the fruit flavor. After several months of storage, the flavor intensity in the beverage with HPBCD - encapsulated flavor remained significantly higher compared to the control beverage without encapsulation. The product also had a more consistent flavor profile over time.

Cosmetic Case: A cosmetic brand was formulating a new anti - aging serum. They incorporated HPBCD to improve the solubility of a key active ingredient. The serum showed better stability during storage, and in consumer trials, users reported better absorption and visible anti - aging effects compared to a similar serum without HPBCD.

Contact Information

If you have any questions or need more information about our Factory Supply Hydroxypropyl - beta - cyclodextrin HPBCD CAS 94035 - 02 - 6/12844

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The Manager has Something to Say

This is William, CEO of Zhishang Chemical Co., Ltd.

Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.

About the company

Vivalr, a paragon of innovation in the chemical sector, fuses cutting - edge R & D with unwavering commitment to quality. Our product spectrum, from industrial stalwarts to fine - tuned chemicals, is a testament to our versatility.

Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
2000 square R&D center
More than 20 research and development personnel,
12 sets of research and development equipment, 10 fume hoods and 6 university laboratories have been developed in cooperation
18 patents, 140 sets of chemical synthesis processes

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
For the United States, Australia, Japan, South Korea, Sweden, France, Spain and other global more than 2000 customers to provide high-quality products and services, has won the recognition and trust of customers in the industry.

More than 12 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

Mode of Transportation

By Air, fast but expensive.

By Sea, usual and economy.

By Train, suit for middle Asia countries.

FAQ

Does it support auditing?

Environmental Protection Science and Technology Park, Zhengfeng Road, High-tech Zone, Jinan City, Shandong Province

Whether to provide samples?

Free samples can be provided, and customers only need to pay the corresponding shipping costs

Delivery time

There are stock in the warehouse, and some products need to be customized for production within 3 working days, depending on the workshop situation and production schedule

What payment methods and currencies are accepted here?

We accept payment methods such as TT, Western Union, and letter of credit, etc. Meanwhile, we support currencies like US dollars, euros, RMB, and Bitcoin, etc.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Vivalr’s delivery rate is guaranteed to be 99.99%

2000+

square meter R&D center

12+

China(set) of R&D equipment

10+

Fume hood

20+

R&D team

User’evaluation of us

"vivalr is my partner for years. Met at 2014 Shanghai CPHI Expo. Not interested then as had stable supplier. In Sep 2016, original supplier couldn't guarantee quality and delivery. Thought of Zhai and his company first. So far, have stable business relationship and good personal friendship."

Marcus Long

" In years of sourcing from China, first found working with Sincere Chemical great. They help in production, delivery and tech, saving time. When first asking Zhai for optical brightener quote, got detailed one with prices, trade details, company info, R&D and production capacity, packaging and raw material control."

Emma Kung

" Hi, I'm Kim, Zhai's partner. Don't like him much (as he never gives more for my prices, haha), but still write customer feedback. Zhai's emails help me understand product and industry. Satisfied with his work ethic. He provides quotes and helps with work details, so I can focus on other things. He's the best supplier for me."

Lisa Phoenix

" Sincere Chemical team visited our USA factory in the year of 2017. We think highly of cooperation with them. We thanked you for the past excellent orders and best product quality. We also talked about some new products for future orders. We will be still in strategic cooperation in the future and help each other."

Marcus Long

"Sincere Chemical is reliable and professional. Its team is excellent in exporting and service, giving suggestions for our new project. Satisfied with service and product quality. Vendor code: 51465768."

Emma Kung

" We are a pharmaceutical manufacturer in Brazil. Happy to cooperate with Sincere Chemical, especially with Zhai. He is patient and friendly. Satisfied with his 24/7 service. We are not only cooperators but also best friends."