The product we are introducing is High - Quality Boc - L - valine with CAS number 13734 - 41 - 3. Boc - L - valine is an important intermediate in organic synthesis. It has a specific chemical structure where the Boc (tert - butoxycarbonyl) group is attached to the amino group of L - valine. The molecular formula of Boc - L - valine is (C_{10}H_{19}NO_{4}). The molecular weight is approximately 217.26 g/mol. This product is usually in the form of a white to off - white crystalline powder. It has good solubility in some organic solvents such as dichloromethane and tetrahydrofuran, while having limited solubility in water.
Boc - L - valine has a wide range of applications in the fields of medicine and biochemistry. In the pharmaceutical industry, it serves as a key building block for the synthesis of various peptides and small - molecule drugs. For example, many anti - cancer and anti - infectious drugs require Boc - L - valine in their synthesis process. It can protect the amino group of valine during peptide synthesis, preventing unwanted side - reactions and ensuring the precise construction of peptide chains. In biochemical research, it is used to study the structure and function of proteins. By incorporating Boc - L - valine into synthetic peptides, researchers can better understand the role of valine residues in protein - ligand interactions and protein folding.
When using Boc - L - valine, it is essential to follow good laboratory practices. First, proper storage is crucial. It should be stored in a cool, dry place away from light and heat. Before use, ensure that the working environment is clean and free from contaminants. In a typical peptide synthesis reaction, Boc - L - valine is usually dissolved in an appropriate organic solvent. The reaction conditions such as temperature, reaction time, and the concentration of reactants need to be carefully controlled. For example, in a coupling reaction with other amino acids, a suitable coupling agent like DCC (dicyclohexylcarbodiimide) or HATU (1 - [bis(dimethylamino)methylene] - 1H - 1,2,3 - triazolo[4,5 - b]pyridinium 3 - oxide hexafluorophosphate) is often used. After the reaction, purification steps such as column chromatography are required to obtain the desired product with high purity.
Case 1: In a research project focused on developing a new anti - cancer peptide drug, Boc - L - valine played a vital role. The research team aimed to synthesize a peptide with specific targeting ability to cancer cells. They used Boc - L - valine as a starting material to construct the peptide chain. By carefully designing the synthesis route and controlling the reaction conditions, they successfully synthesized the target peptide. In in vitro cell experiments, the peptide showed significant inhibitory effects on the growth of cancer cells. Further in vivo experiments in animal models also demonstrated its anti - cancer efficacy, indicating that Boc - L - valine was an indispensable component in this synthesis process.
Case 2: A biochemistry research group was studying the interaction between a protein and a small - molecule ligand. They synthesized a series of peptides containing Boc - L - valine to mimic the binding site of the protein. Through techniques such as NMR spectroscopy and X - ray crystallography, they were able to determine the detailed structure of the peptide - ligand complex. This information provided valuable insights into the mechanism of protein - ligand interaction, which is important for drug design and development.
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